Detalhe da pesquisa
1.
Functional restoration of a CFTR splicing mutation through RNA delivery of CRISPR adenine base editor.
Mol Ther
; 31(6): 1647-1660, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36895161
2.
Pharmacoproteomics pinpoints HSP70 interaction for correction of the most frequent Wilson disease-causing mutant of ATP7B.
Proc Natl Acad Sci U S A
; 117(51): 32453-32463, 2020 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33288711
3.
KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model.
Physiol Genomics
; 54(7): 273-282, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35658672
4.
Esc peptides as novel potentiators of defective cystic fibrosis transmembrane conductance regulator: an unprecedented property of antimicrobial peptides.
Cell Mol Life Sci
; 79(1): 67, 2021 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34971429
5.
The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs.
Int J Mol Sci
; 23(6)2022 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35328596
6.
Chloride transport modulators as drug candidates.
Am J Physiol Cell Physiol
; 321(6): C932-C946, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34644122
7.
Structure and function of TMEM16 proteins (anoctamins).
Physiol Rev
; 94(2): 419-59, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24692353
8.
Comprehensive Analysis of Combinatorial Pharmacological Treatments to Correct Nonsense Mutations in the CFTR Gene.
Int J Mol Sci
; 22(21)2021 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769402
9.
Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment.
Int J Mol Sci
; 22(10)2021 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34067708
10.
Two CFTR mutations within codon 970 differently impact on the chloride channel functionality.
Hum Mutat
; 40(6): 742-748, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30851139
11.
TRPV4 and purinergic receptor signalling pathways are separately linked in airway epithelia to CFTR and TMEM16A chloride channels.
J Physiol
; 597(24): 5859-5878, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31622498
12.
High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel.
J Biol Chem
; 293(4): 1203-1217, 2018 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29158263
13.
Peripheral localization of the epithelial sodium channel in the apical membrane of bronchial epithelial cells.
Exp Physiol
; 104(6): 866-875, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30924990
14.
CFTR pharmacology.
Cell Mol Life Sci
; 74(1): 117-128, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27704174
15.
Speeding Up the Identification of Cystic Fibrosis Transmembrane Conductance Regulator-Targeted Drugs: An Approach Based on Bioinformatics Strategies and Surface Plasmon Resonance.
Molecules
; 23(1)2018 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29316712
16.
Functional analysis of acid-activated Clâ» channels: properties and mechanisms of regulation.
Biochim Biophys Acta
; 1848(1 Pt A): 105-14, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25306966
17.
Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6).
FASEB J
; 29(1): 152-63, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25351986
18.
Phenylhydrazones as Correctors of a Mutant Cystic Fibrosis Transmembrane Conductance Regulator.
Arch Pharm (Weinheim)
; 349(2): 112-23, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26701662
19.
Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms.
J Physiol
; 593(17): 3829-48, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26108457
20.
Non-canonical translation start sites in the TMEM16A chloride channel.
Biochim Biophys Acta
; 1838(1 Pt B): 89-97, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23994600