Detalhe da pesquisa
1.
NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin.
Mol Pharm
; 20(1): 370-382, 2023 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36484496
2.
A concise synthesis of 3-substituted-7-amino-6-carboxyl-8-azachromones.
Tetrahedron Lett
; 60(30): 2035-2037, 2019 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32831416
3.
Synthesis of deuterium-labelled amlexanox and its metabolic stability against mouse, rat, and human microsomes.
J Labelled Comp Radiopharm
; 62(5): 202-208, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30828860
4.
Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition.
Mol Pharmacol
; 94(4): 1210-1219, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30082428
5.
Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity.
Bioorg Med Chem
; 26(20): 5443-5461, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30270002
6.
PF-04859989 as a template for structure-based drug design: identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency.
Bioorg Med Chem Lett
; 23(7): 1961-6, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23466229
7.
A general strategy for the synthesis of cyclic N-aryl hydroxamic acids via partial nitro group reduction.
J Org Chem
; 76(9): 3484-97, 2011 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21452845
8.
Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition.
Bioorg Med Chem Lett
; 18(8): 2562-6, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18387300
9.
Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions.
ACS Med Chem Lett
; 4(1): 37-40, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900560
10.
Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia.
ACS Med Chem Lett
; 3(3): 187-92, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900455
11.
N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-N-alkylsulfonamides as peripherally restricted N-methyl-D-aspartate receptor antagonists for the treatment of pain.
Bioorg Med Chem Lett
; 17(16): 4599-603, 2007 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17562362
12.
Formation of a layered framework structure based upon 4-methyl-2,6-bis(methylphosphonic acid) phenol.
Dalton Trans
; (32): 3912-7, 2006 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16896452
13.
A three-dimensional framework structure constructed from 2-(2-pyridyl-N-oxide) ethylphosphonic acid and Nd(III).
Inorg Chem
; 45(9): 3741-5, 2006 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16634609
14.
Features of the thermodynamics of two-phase distribution reactions of americium(III) and europium(III) nitrates into solutions of 2,6-bis[(bis(2-ethylhexyl)phosphino)methyl]pyridine N,P,P'-trioxide.
Inorg Chem
; 41(22): 5849-58, 2002 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12401093
15.
Hydrogen bonded framework structures constructed from 2-(pyridyl N-oxide) methylphosphonic acid ligands and erbium(III).
Inorg Chem
; 43(7): 2443-8, 2004 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15046522