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1.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1569239

RESUMO

Objetivo: Validar el contenido de un cuestionario de auto-reporte en español para explorar actitudes, prácticas y barreras de odontólogos no especialistas en periodoncia frente al diagnóstico y tratamiento de problemas periodontales y criterios para derivar. Materiales y métodos: Seis especialistas en periodoncia de cinco países latinoamericanos construyeron versión#1 de un cuestionario. 21 expertos de tres áreas disciplinares de 6 países valoraron de 1 a 5 (1: totalmente en desacuerdo, 5: totalmente de acuerdo) cada ítem en su pertinencia, relevancia, claridad y coherencia. Según grado de acuerdo se reformuló cada ítem y se construyó versión#2 que fue piloteada en 60 odontólogos no especialistas en periodoncia, 3 de ellos fueron entrevistados para evaluar la comprensión y semántica. Luego del análisis se elaboró la versión final (versión#3). Resultados: Los ítems formulados de versión#1 tuvieron una valoración promedio de 4,6 (rango 3.7-5). Fueron reformulados evitando palabras confusas y que tuvieran aceptación transversal en países participantes, se eliminó ítem con menor puntuación de acuerdo de expertos. La aplicación de versión#2 tuvo un tiempo de respuesta de 12 minutos, se reformularon opciones y agregaron 4 ítems para obtener la versión final con 44 preguntas. Conclusiones: Se construyó un cuestionario de auto-reporte con validez de contenido para evaluar actitudes y prácticas en salud-enfermedad periodontal en odontólogos generales o no especialistas en periodoncia de habla hispana.


Aim: T o validate the content of a self-report questionnaire in Spanish to explore attitudes, practices and barriers of dentists non-specialized in periodontics when facing the diagnosis and treatment of periodontal problems and criteria for referral. Materials and methods: Six specialists in periodontics from five Latin American countries constructed version#1 of a questionnaire. Twenty-one experts from 3 disciplinary areas from 6 countries rated each item from 1 to 5 (1: totally disagree, 5: totally agree) regarding its appropriateness, relevance, clarity, and coherence. According to the degree of agreement, the item was reformulated, and version #2 was built, which was tested on 60 dentists non-specialized in periodontics. Then, 3 of them were interviewed to assess comprehension and semantics. After analysis, the final version was prepared (version#3). Results: The items formulated in version#1 had an average score of 4.6 (range 3.7-5). Questions and options were reformulated, avoiding confusing words and having transversal acceptance in the participating countries. The items with the lowest degree of expert agreement were eliminated. The application of version#2 had a response time of 12 minutes, options were reformulated, and 4 items were added to obtain the final version with 44 questions. Conclusions: A self-report questionnaire with content validity was constructed to assess attitudes and practices in periodontal health and disease in Spanish-speaking general dentists or non-specialists in periodontics.

2.
J Appl Oral Sci ; 26: e20170075, 2018 Jan 18.
Artigo em Inglês | MEDLINE | ID: mdl-29364340

RESUMO

The aim of this double-blind, placebo-controlled and parallel- arm randomized clinical trial was to evaluate the effects of Lactobacillus rhamnosus SP1-containing probiotic sachet and azithromycin tablets as an adjunct to nonsurgical therapy in clinical parameters and in presence and levels of Tannerella forsythia, Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. Forty-seven systemically healthy volunteers with chronic periodontitis were recruited and monitored clinically and microbiologically at baseline for 3, 6 and 9 months after therapy. Subgingival plaque samples were collected from four periodontal sites with clinical attachment level ≥1 mm, probing pocket depth ≥4 mm and bleeding on probing, one site in each quadrant. Samples were cultivated and processed using the PCR technique. Patients received nonsurgical therapy including scaling and root planing (SRP) and were randomly assigned to a probiotic (n=16), antibiotic (n = 16) or placebo (n = 15) group. L. rhamnosus SP1 was taken once a day for 3 months. Azithromycin 500mg was taken once a day for 5 days. All groups showed improvements in clinical and microbiological parameters at all time points evaluated. Probiotic and antibiotic groups showed greater reductions in cultivable microbiota compared with baseline. The placebo group showed greater reduction in number of subjects with P. gingivalis compared with baseline. However, there were no significant differences between groups. The adjunctive use of L. rhamnosus SP1 sachets and azithromycin during initial therapy resulted in similar clinical and microbiological improvements compared with the placebo group.


Assuntos
Antibacterianos/uso terapêutico , Azitromicina/uso terapêutico , Periodontite Crônica/tratamento farmacológico , Lacticaseibacillus rhamnosus/química , Probióticos/uso terapêutico , Adulto , Aggregatibacter actinomycetemcomitans/efeitos dos fármacos , Aggregatibacter actinomycetemcomitans/isolamento & purificação , Análise de Variância , Antibacterianos/farmacologia , Azitromicina/farmacologia , Contagem de Colônia Microbiana , Placa Dentária/tratamento farmacológico , Placa Dentária/microbiologia , Raspagem Dentária/métodos , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Índice Periodontal , Efeito Placebo , Reação em Cadeia da Polimerase , Porphyromonas gingivalis/efeitos dos fármacos , Porphyromonas gingivalis/isolamento & purificação , Probióticos/farmacologia , Estatísticas não Paramétricas , Tannerella forsythia/efeitos dos fármacos , Tannerella forsythia/isolamento & purificação , Fatores de Tempo , Resultado do Tratamento
3.
J. appl. oral sci ; 26: e20170075, 2018. tab, graf
Artigo em Inglês | LILACS, BBO - odontologia (Brasil) | ID: biblio-893719

RESUMO

ABSTRACT Objective: The aim of this double-blind, placebo-controlled and parallel- arm randomized clinical trial was to evaluate the effects of Lactobacillus rhamnosus SP1-containing probiotic sachet and azithromycin tablets as an adjunct to nonsurgical therapy in clinical parameters and in presence and levels of Tannerella forsythia, Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. Material and Methods: Forty-seven systemically healthy volunteers with chronic periodontitis were recruited and monitored clinically and microbiologically at baseline for 3, 6 and 9 months after therapy. Subgingival plaque samples were collected from four periodontal sites with clinical attachment level ≥1 mm, probing pocket depth ≥4 mm and bleeding on probing, one site in each quadrant. Samples were cultivated and processed using the PCR technique. Patients received nonsurgical therapy including scaling and root planing (SRP) and were randomly assigned to a probiotic (n=16), antibiotic (n = 16) or placebo (n = 15) group. L. rhamnosus SP1 was taken once a day for 3 months. Azithromycin 500mg was taken once a day for 5 days. Results: All groups showed improvements in clinical and microbiological parameters at all time points evaluated. Probiotic and antibiotic groups showed greater reductions in cultivable microbiota compared with baseline. The placebo group showed greater reduction in number of subjects with P. gingivalis compared with baseline. However, there were no significant differences between groups. Conclusions: The adjunctive use of L. rhamnosus SP1 sachets and azithromycin during initial therapy resulted in similar clinical and microbiological improvements compared with the placebo group.


Assuntos
Humanos , Masculino , Feminino , Adulto , Azitromicina/uso terapêutico , Probióticos/uso terapêutico , Lacticaseibacillus rhamnosus/química , Periodontite Crônica/tratamento farmacológico , Antibacterianos/uso terapêutico , Fatores de Tempo , Contagem de Colônia Microbiana , Efeito Placebo , Índice Periodontal , Reação em Cadeia da Polimerase , Método Duplo-Cego , Análise de Variância , Raspagem Dentária/métodos , Resultado do Tratamento , Aggregatibacter actinomycetemcomitans/isolamento & purificação , Aggregatibacter actinomycetemcomitans/efeitos dos fármacos , Azitromicina/farmacologia , Porphyromonas gingivalis/isolamento & purificação , Porphyromonas gingivalis/efeitos dos fármacos , Estatísticas não Paramétricas , Probióticos/farmacologia , Placa Dentária/microbiologia , Placa Dentária/tratamento farmacológico , Tannerella forsythia/isolamento & purificação , Tannerella forsythia/efeitos dos fármacos , Pessoa de Meia-Idade , Antibacterianos/farmacologia
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