Detalhe da pesquisa
1.
Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.
Immunity
; 47(1): 183-198.e6, 2017 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28723550
2.
DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression.
EMBO Rep
; 24(8): e56233, 2023 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37382163
3.
Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.
Immunity
; 52(2): 417-418, 2020 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32075730
4.
DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons.
Cereb Cortex
; 33(19): 10272-10285, 2023 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37566909
5.
Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease.
Proc Natl Acad Sci U S A
; 116(19): 9622-9627, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31015293
6.
Reprint of: Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease.
Neurobiol Dis
; 135: 104744, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31931139
7.
Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle.
PLoS Biol
; 15(2): e1002597, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28207742
8.
Manipulation of microbiota reveals altered callosal myelination and white matter plasticity in a model of Huntington disease.
Neurobiol Dis
; 127: 65-75, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30802499
9.
Connectomic imaging reveals Huntington-related pathological and pharmaceutical effects in a mouse model.
NMR Biomed
; 31(12): e4007, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30260561
10.
Environmental Deprivation Effects on Myelin Ultrastructure in Huntington Disease and Wildtype Mice.
Mol Neurobiol
; 2023 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38079108
11.
Dysregulated COMT Expression in Fragile X Syndrome.
Neuromolecular Med
; 25(4): 644-649, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37684514
12.
Nucleophosmin 1 cooperates with the methyltransferase DOT1L to preserve peri-nucleolar heterochromatin organization by regulating H3K27me3 levels and DNA repeats expression.
Epigenetics Chromatin
; 16(1): 36, 2023 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37759327
13.
Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult.
Brain Pathol
; 32(5): e13064, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35285112
14.
Abnormal Spinal Cord Myelination due to Oligodendrocyte Dysfunction in a Model of Huntington's Disease.
J Huntingtons Dis
; 10(3): 377-384, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34366364
15.
Integrative Analysis Identifies Key Molecular Signatures Underlying Neurodevelopmental Deficits in Fragile X Syndrome.
Biol Psychiatry
; 88(6): 500-511, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32653109
16.
Laquinimod Treatment Improves Myelination Deficits at the Transcriptional and Ultrastructural Levels in the YAC128 Mouse Model of Huntington Disease.
Mol Neurobiol
; 56(6): 4464-4478, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-30334188
17.
Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse.
Mol Neurodegener
; 13(1): 25, 2018 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29783994
18.
Early pridopidine treatment improves behavioral and transcriptional deficits in YAC128 Huntington disease mice.
JCI Insight
; 2(23)2017 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29212949
19.
Treatment with the MAO-A inhibitor clorgyline elevates monoamine neurotransmitter levels and improves affective phenotypes in a mouse model of Huntington disease.
Exp Neurol
; 278: 4-10, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26825854
20.
Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease.
Sci Rep
; 6: 31652, 2016 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27528441