Pesquisa | Biblioteca Virtual em Saúde

1.

Srebp-controlled glucose metabolism is essential for NK cell functional responses.

Assmann, Nadine; O'Brien, Katie L; Donnelly, Raymond P; Dyck, Lydia; Zaiatz-Bittencourt, Vanessa; Loftus, Róisín M; Heinrich, Paul; Oefner, Peter J; Lynch, Lydia; Gardiner, Clair M; Dettmer, Katja; Finlay, David K.

Nat Immunol ; 18(11): 1197-1206, 2017 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-28920951

2.

How to wake a killer.

Gardiner, Clair M.

Nat Immunol ; 20(12): 1561-1563, 2019 12.

Artigo em Inglês | MEDLINE | ID: mdl-31659329

3.

De novo polyamine synthesis supports metabolic and functional responses in activated murine NK cells.

O'Brien, Katie L; Assmann, Nadine; O'Connor, Eimear; Keane, Cathal; Walls, Jessica; Choi, Chloe; Oefner, Peter J; Gardiner, Clair M; Dettmer, Katja; Finlay, David K.

Eur J Immunol ; 51(1): 91-102, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-32946110

4.

Canonical TGF-ß Signaling Pathway Represses Human NK Cell Metabolism.

Zaiatz-Bittencourt, Vanessa; Finlay, David K; Gardiner, Clair M.

J Immunol ; 200(12): 3934-3941, 2018 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-29720425

5.

The cells that mediate innate immune memory and their functional significance in inflammatory and infectious diseases.

Gardiner, Clair M; Mills, Kingston H G.

Semin Immunol ; 28(4): 343-50, 2016 08.

Artigo em Inglês | MEDLINE | ID: mdl-26979658

6.

Metabolic Reprogramming Supports IFN-Î³ Production by CD56bright NK Cells.

Keating, Sinéad E; Zaiatz-Bittencourt, Vanessa; Loftus, Roisín M; Keane, Ciara; Brennan, Kiva; Finlay, David K; Gardiner, Clair M.

J Immunol ; 196(6): 2552-60, 2016 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-26873994

7.

Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults.

Deac, Oana M; Mills, James L; Gardiner, Clair M; Shane, Barry; Quinn, Louise; Midttun, Øivind; McCann, Adrian; Meyer, Klaus; Ueland, Per M; Fan, Ruzong; Lu, Zhaohui; Brody, Lawrence C; Molloy, Anne M.

J Nutr ; 146(9): 1801-6, 2016 09.

Artigo em Inglês | MEDLINE | ID: mdl-27489009

8.

mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.

Donnelly, Raymond P; Loftus, Róisín M; Keating, Sinéad E; Liou, Kevin T; Biron, Christine A; Gardiner, Clair M; Finlay, David K.

J Immunol ; 193(9): 4477-84, 2014 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-25261477

9.

Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection.

Dring, Megan M; Morrison, Maria H; McSharry, Brian P; Guinan, Kieran J; Hagan, Richard; O'Farrelly, Cliona; Gardiner, Clair M.

Proc Natl Acad Sci U S A ; 108(14): 5736-41, 2011 Apr 05.

Artigo em Inglês | MEDLINE | ID: mdl-21402922

10.

Common HIV-1 peptide variants mediate differential binding of KIR3DL1 to HLA-Bw4 molecules.

Fadda, Lena; O'Connor, Geraldine M; Kumar, Swati; Piechocka-Trocha, Alicja; Gardiner, Clair M; Carrington, Mary; McVicar, Daniel W; Altfeld, Marcus.

J Virol ; 85(12): 5970-4, 2011 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-21471246

11.

Heightened metabolic responses in NK cells from patients with neuroblastoma suggests increased potential for immunotherapy.

Slattery, Karen; Breheny, Megan; Woods, Elena; Keating, Sinead; Brennan, Kiva; Rooney, Caroline; Augustine, Sindhu; Ryan, Aishling; Owens, Cormac; Gardiner, Clair M.

Front Oncol ; 12: 1004871, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36276144

12.

NK cells and psoriasis.

Dunphy, Sinéad; Gardiner, Clair M.

J Biomed Biotechnol ; 2011: 248317, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21687543

13.

Cytokine-induced natural killer cell training is dependent on cellular metabolism and is defective in obesity.

Kedia-Mehta, Nidhi; Tobin, Laura; Zaiatz-Bittencourt, Vanessa; Pisarska, Marta M; De Barra, Conor; Choi, Chloe; Elamin, Einas; O'Shea, Donal; Gardiner, Clair M; Finlay, David K; Hogan, Andrew E.

Blood Adv ; 5(21): 4447-4455, 2021 11 09.

Artigo em Inglês | MEDLINE | ID: mdl-34607345

14.

TGFß drives NK cell metabolic dysfunction in human metastatic breast cancer.

Slattery, Karen; Woods, Elena; Zaiatz-Bittencourt, Vanessa; Marks, Sam; Chew, Sonya; Conroy, Michael; Goggin, Caitriona; MacEochagain, Colm; Kennedy, John; Lucas, Sophie; Finlay, David K; Gardiner, Clair M.

J Immunother Cancer ; 9(2)2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33568351

15.

Specific human cytomegalovirus signature detected in NK cell metabolic changes post vaccination.

Woods, Elena; Zaiatz-Bittencourt, Vanessa; Bannan, Ciaran; Bergin, Colm; Finlay, David K; Hoffmann, Matthias; Brown, Anthony; Turner, Bethany; Makvandi-Nejad, Shokouh; Vassilev, Ventzi; Capone, Stefania; Folgori, Antonella; Hanke, Tomás; Barnes, Eleanor; Dorrell, Lucy; Gardiner, Clair M.

NPJ Vaccines ; 6(1): 117, 2021 Sep 28.

Artigo em Inglês | MEDLINE | ID: mdl-34584101

16.

Metabolic but not transcriptional regulation by PKM2 is important for natural killer cell responses.

Walls, Jessica F; Subleski, Jeff J; Palmieri, Erika M; Gonzalez-Cotto, Marieli; Gardiner, Clair M; McVicar, Daniel W; Finlay, David K.

Elife ; 92020 08 19.

Artigo em Inglês | MEDLINE | ID: mdl-32812866

17.

NK cell metabolism.

Gardiner, Clair M.

J Leukoc Biol ; 105(6): 1235-1242, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-30676653

18.

NK Cell Metabolism and TGFß - Implications for Immunotherapy.

Slattery, Karen; Gardiner, Clair M.

Front Immunol ; 10: 2915, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31921174

19.

Suppression of Natural Killer cell NKG2D and CD226 anti-tumour cascades by platelet cloaked cancer cells: Implications for the metastatic cascade.

Cluxton, Christopher D; Spillane, Cathy; O'Toole, Sharon A; Sheils, Orla; Gardiner, Clair M; O'Leary, John J.

PLoS One ; 14(3): e0211538, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-30908480

20.

Natural Killer Cells Integrate Signals Received from Tumour Interactions and IL2 to Induce Robust and Prolonged Anti-Tumour and Metabolic Responses.

Kedia-Mehta, Nidhi; Choi, Chloe; McCrudden, Aisling; Littwitz-Salomon, Elisabeth; Fox, Proinnsias G; Gardiner, Clair M; Finlay, David K.

Immunometabolism ; 1: e190014, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31595191

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