Detalhe da pesquisa
1.
Regulation of GTPase function by autophosphorylation.
Mol Cell
; 82(5): 950-968.e14, 2022 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35202574
2.
Biochemical and biophysical characterization of the RAS family small GTPase protein DiRAS3.
Protein Expr Purif
; 212: 106361, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37652393
3.
NMR in integrated biophysical drug discovery for RAS: past, present, and future.
J Biomol NMR
; 74(10-11): 531-554, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32804298
4.
Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
Proc Natl Acad Sci U S A
; 112(21): 6625-30, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25941399
5.
Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1).
J Biol Chem
; 291(30): 15641-52, 2016 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226556
6.
Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
Proc Natl Acad Sci U S A
; 109(16): 6078-83, 2012 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22474372
7.
Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts.
Methods
; 57(4): 473-85, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22750304
8.
Structures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant.
J Mol Biol
; 434(9): 167527, 2022 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35257782
9.
Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics.
J Biol Chem
; 285(8): 5132-6, 2010 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20018863
10.
Real-time NMR study of guanine nucleotide exchange and activation of RhoA by PDZ-RhoGEF.
J Biol Chem
; 285(8): 5137-45, 2010 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20018869
11.
Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine-dependent interface: a model for KRAS oligomerization.
Chem Sci
; 12(38): 12827-12837, 2021 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34703570
12.
Type 2 ryanodine receptor domain A contains a unique and dynamic α-helix that transitions to a ß-strand in a mutant linked with a heritable cardiomyopathy.
J Mol Biol
; 425(21): 4034-46, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23978697
13.
The solution structure of the C-terminal Ig-like domain of the bacteriophage λ tail tube protein.
J Mol Biol
; 403(3): 468-79, 2010 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20826161