Detalhe da pesquisa
1.
Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/- mouse model.
Proc Natl Acad Sci U S A
; 114(12): 3151-3156, 2017 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28265066
2.
HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.
Blood
; 121(26): 5158-66, 2013 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23667053
3.
Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells.
Nucleic Acids Res
; 37(7): e55, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19279185
4.
MDM4 is a key therapeutic target in cutaneous melanoma.
Nat Med
; 18(8): 1239-47, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22820643
5.
Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo.
Mol Cell Biol
; 30(22): 5394-405, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20855528
6.
Negative and positive regulation of MAPK phosphatase 3 controls platelet-derived growth factor-induced Erk activation.
J Biol Chem
; 284(7): 4626-34, 2009 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19106095