Detalhe da pesquisa
1.
In vitro efficacy of 2,N-bisarylated 2-ethoxyacetamides against Plasmodium falciparum.
Bioorg Med Chem Lett
; 26(3): 1048-1051, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26750257
2.
Synthesis and In vitro Efficacy of Tetracyclic Benzothiazepines Against Blood-Stage Plasmodium falciparum and Liver-Stage P. berghei.
Med Chem
; 19(5): 478-484, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993460
3.
Comparison of the in vitro invasive capabilities of Plasmodium falciparum schizonts isolated by Percoll gradient or using magnetic based separation.
Malar J
; 10: 96, 2011 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21501476
4.
Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice.
Malar J
; 10: 150, 2011 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21645370
5.
In vitro efficacy of 7-benzylamino-1-isoquinolinamines against Plasmodium falciparum related to the efficacy of chalcones.
Bioorg Med Chem Lett
; 21(2): 786-9, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21168330
6.
In vitro biotransformation, in vivo efficacy and pharmacokinetics of antimalarial chalcones.
Pharmacology
; 87(1-2): 96-104, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21282967
7.
Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum.
Antimicrob Agents Chemother
; 54(6): 2455-64, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20350946
8.
Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols.
Malar J
; 9: 51, 2010 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20149249
9.
Structure-activity relationships amongst 4-position quinoline methanol antimalarials that inhibit the growth of drug sensitive and resistant strains of Plasmodium falciparum.
Bioorg Med Chem Lett
; 20(4): 1347-51, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20097070
10.
Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones.
Bioorg Med Chem Lett
; 19(7): 1982-5, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19250824
11.
Synthesis and biological evaluation of the first pentafluorosulfanyl analogs of mefloquine.
Org Biomol Chem
; 7(20): 4163-5, 2009 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19795052
12.
Antimalarial activity of phenylthiazolyl-bearing hydroxamate-based histone deacetylase inhibitors.
Antimicrob Agents Chemother
; 52(10): 3467-77, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18644969
13.
Synthesis and antimalarial activity of new isotebuquine analogues.
J Med Chem
; 50(4): 889-96, 2007 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17266295
14.
Synthesis and antiprotozoal activity of some 2-(trifluoromethyl)-1H-benzimidazole bioisosteres.
Eur J Med Chem
; 41(1): 135-41, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16260067
15.
Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model.
Sci Rep
; 6: 21216, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26880111
16.
Antimalarial activity of 4-amidinoquinoline and 10-amidinobenzonaphthyridine derivatives.
J Med Chem
; 58(8): 3411-31, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25654185
17.
Design, synthesis, and evaluation of new chemosensitizers in multi-drug-resistant Plasmodium falciparum.
J Med Chem
; 45(13): 2741-8, 2002 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12061877
18.
Mixed steroidal 1,2,4,5-tetraoxanes: antimalarial and antimycobacterial activity.
J Med Chem
; 45(16): 3331-6, 2002 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12139444
19.
Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.
J Med Chem
; 46(18): 3877-82, 2003 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-12930149
20.
Polymorphism of the Plasmodium falciparum multidrug resistance and chloroquine resistance transporter genes and in vitro susceptibility to aminoquinolines in isolates from the Peruvian Amazon.
Am J Trop Med Hyg
; 70(5): 461-6, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15155976