Detalhe da pesquisa
1.
Synthesis and in vitro antitumor evaluation of new thieno[2,3-d]pyrimidine derivatives as EGFR and DHFR inhibitors.
Bioorg Chem
; 148: 107401, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38749115
2.
Synthesis, molecular modeling simulations and anticancer activity of some new Imidazo[2,1-b]thiazole analogues as EGFR/HER2 and DHFR inhibitors.
Bioorg Chem
; 150: 107538, 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38861913
3.
Design, synthesis, and evaluation of new benzimidazole thiourea derivatives as antitumor agents.
Arch Pharm (Weinheim)
; 356(11): e2300269, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37602810
4.
Design, synthesis, and antitumor screening of new thiazole, thiazolopyrimidine, and thiazolotriazine derivatives as potent inhibitors of VEGFR-2.
Drug Dev Res
; 84(8): 1664-1698, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37661648
5.
Carbonic Anhydrase Inhibition Activities of Schiff's Bases Based on Quinazoline-Linked Benzenesulfonamide.
Molecules
; 27(22)2022 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36431826
6.
Synthesis, Characterization, and Biological Evaluation of Some Novel Pyrazolo[5,1-b]thiazole Derivatives as Potential Antimicrobial and Anticancer Agents.
Molecules
; 26(17)2021 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34500816
7.
The novel economical synthesis and antimicrobial activity of a trithiocarbonate derivative.
Bioorg Chem
; 91: 103157, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31421509
8.
Design and synthesis of new substituted spirooxindoles as potential inhibitors of the MDM2-p53 interaction.
Bioorg Chem
; 86: 598-608, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30802707
9.
SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX.
Bioorg Chem
; 83: 549-558, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30471577
10.
A Simple, Efficient, and Eco-Friendly Method for the Preparation of 3-Substituted-2,3-dihydroquinazolin-4(1H)-one Derivatives.
Molecules
; 24(22)2019 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31717480
11.
Synthesis and Anti-Proliferative Assessment of Triazolo-Thiadiazepine and Triazolo-Thiadiazine Scaffolds.
Molecules
; 24(24)2019 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31817609
12.
Synthesis and Spectroscopic Identification of Certain Imidazole-Semicarbazone Conjugates Bearing Benzodioxole Moieties: New Antifungal Agents.
Molecules
; 24(1)2019 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30621111
13.
Anticancer Indole-Based Chalcones: A Structural and Theoretical Analysis.
Molecules
; 24(20)2019 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31623155
14.
Effect of hydroxylated solvents on the active constituents of Salvadora persica root "Siwak".
Saudi Pharm J
; 27(2): 220-224, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30766432
15.
Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer.
Bioorg Chem
; 77: 443-456, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29453076
16.
One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells.
J Enzyme Inhib Med Chem
; 33(1): 309-318, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29281924
17.
Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and in vitro biological evaluation.
J Enzyme Inhib Med Chem
; 33(1): 686-700, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29560733
18.
Synthesis, Crystal Structure and DFT Studies of a New Dinuclear Ag(I)-Malonamide Complex.
Molecules
; 23(4)2018 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29641507
19.
A One-Pot Biginelli Synthesis and Characterization of Novel Dihydropyrimidinone Derivatives Containing Piperazine/Morpholine Moiety.
Molecules
; 23(7)2018 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29954138
20.
Synthesis of bulky-tailed sulfonamides incorporating pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-1(5H)-yl) moieties and evaluation of their carbonic anhydrases I, II, IV and IX inhibitory effects.
Bioorg Med Chem
; 25(7): 2210-2217, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28256371