Detalhe da pesquisa
1.
Whole cell screen based identification of spiropiperidines with potent antitubercular properties.
Bioorg Med Chem Lett
; 25(16): 3234-45, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26087937
2.
Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy.
Bioorg Med Chem Lett
; 24(3): 870-9, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24405701
3.
2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy.
J Med Chem
; 2024 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38918002
4.
Recent developments of imidazo[1,2-a]pyridine analogues as antituberculosis agents.
RSC Med Chem
; 14(4): 644-657, 2023 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37122538
5.
Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity.
J Med Chem
; 65(9): 6903-6925, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35500229
6.
1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis.
ACS Infect Dis
; 8(11): 2315-2326, 2022 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36325756
7.
Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies.
J Med Chem
; 64(1): 719-740, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33395287
8.
1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis.
J Med Chem
; 64(17): 12790-12807, 2021 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34414766
9.
Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification Studies.
J Med Chem
; 60(24): 10118-10134, 2017 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29148755
10.
A convenient method for the conversion of N-acyloxazolidinones to hydroxamic acids.
Org Lett
; 4(20): 3343-6, 2002 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-12323014
11.
4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.
J Med Chem
; 57(12): 5419-34, 2014 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24871036
12.
Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase B.
J Med Chem
; 56(21): 8834-48, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24088190
13.
Binding of matrix metalloproteinase inhibitors to extracellular matrix: 3D-QSAR analysis.
Chem Biol Drug Des
; 72(4): 237-48, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18844670