Detalhe da pesquisa
1.
Considerations when deriving compound-specific limits for extractables and leachables from pharmaceutical products: Four case studies.
Regul Toxicol Pharmacol
; 118: 104802, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33038429
2.
Skin sensitization in silico protocol.
Regul Toxicol Pharmacol
; 116: 104688, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32621976
3.
Managing emerging mutagenicity risks: Late stage mutagenic impurity control within the atovaquone second generation synthesis.
Regul Toxicol Pharmacol
; 99: 22-32, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30118726
4.
It's difficult, but important, to make negative predictions.
Regul Toxicol Pharmacol
; 76: 79-86, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26785392
5.
Evaluation of a statistics-based Ames mutagenicity QSAR model and interpretation of the results obtained.
Regul Toxicol Pharmacol
; 76: 7-20, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26708083
6.
Evaluation of aromatic amines with different purities and different solvent vehicles in the Ames test.
Regul Toxicol Pharmacol
; 71(2): 244-50, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25542092
7.
In vitro assays for induction of drug metabolism.
Methods Mol Biol
; 481: 47-58, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19096794
8.
Effect of Pyrethrins on cytochrome P450 forms in cultured rat and human hepatocytes.
Toxicology
; 243(1-2): 84-95, 2008 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18022748
9.
Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS.
ACS Med Chem Lett
; 9(7): 623-628, 2018 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30034590
10.
International Pig-a gene mutation assay trial (stage III): results with N-methyl-N-nitrosourea.
Environ Mol Mutagen
; 52(9): 699-710, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22167885
11.
International Pig-a gene mutation assay trial: evaluation of transferability across 14 laboratories.
Environ Mol Mutagen
; 52(9): 690-8, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21910140
12.
Structure based drug design: development of potent and selective factor IXa (FIXa) inhibitors.
J Med Chem
; 53(4): 1473-82, 2010 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20121197