Detalhe da pesquisa
1.
Engineering and Expression Strategies for Optimization of L-Asparaginase Development and Production.
Int J Mol Sci
; 24(20)2023 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37894901
2.
Cytoprotective Activity of Polyamines Is Associated with the Alternative Splicing of RAD51A Pre-mRNA in Normal Human CD4+ T Lymphocytes.
Int J Mol Sci
; 23(3)2022 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163785
3.
Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes.
Biochem Biophys Res Commun
; 509(3): 790-796, 2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30612734
4.
Murine regulatory T cells induce death of effector T, B, and NK lymphocytes through a contact-independent mechanism involving telomerase suppression and telomere-associated senescence.
Cell Immunol
; 331: 146-160, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29935763
5.
Rhodospirillum rubruml-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition.
Biochem Biophys Res Commun
; 492(2): 282-288, 2017 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28837806
6.
Electrochemical approach for the analysis of DNA degradation in native DNA and apoptotic cells.
Heliyon
; 10(3): e25602, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38371963
7.
Induction of FoxP3 Pre-mRNA Alternative Splicing to Enhance the Suppressive Activity of Regulatory T Cells from Amyotrophic Lateral Sclerosis Patients.
Biomedicines
; 12(5)2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38790984
8.
Modulation of Suppressive Activity and Proliferation of Human Regulatory T Cells by Splice-Switching Oligonucleotides Targeting FoxP3 Pre-mRNA.
Cells
; 13(1)2023 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38201281
9.
New Genetic Bomb Trigger: Design, Synthesis, Molecular Dynamics Simulation, and Biological Evaluation of Novel BIBR1532-Related Analogs Targeting Telomerase against Non-Small Cell Lung Cancer.
Pharmaceuticals (Basel)
; 15(4)2022 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35455478
10.
Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.
J Med Chem
; 64(15): 11432-11444, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34283610
11.
Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes.
Biochimie
; 174: 34-43, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315661
12.
Endonuclease G modulates the alternative splicing of deoxyribonuclease 1 mRNA in human CD4+ T lymphocytes and prevents the progression of apoptosis.
Biochimie
; 157: 158-176, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30521874
13.
Contact-independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis.
Mol Immunol
; 101: 229-244, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30025223
14.
Inhibition of telomerase activity and induction of apoptosis by Rhodospirillum rubrum L-asparaginase in cancer Jurkat cell line and normal human CD4+ T lymphocytes.
Cancer Med
; 6(11): 2697-2712, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28984046