Detalhe da pesquisa
1.
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Nat Chem Biol
; 16(1): 50-59, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31819276
2.
Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Nat Chem Biol
; 16(4): 479, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32139909
3.
Benchmarking network algorithms for contextualizing genes of interest.
PLoS Comput Biol
; 15(12): e1007403, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31860671
4.
Application of Large-Scale Aptamer-Based Proteomic Profiling to Planned Myocardial Infarctions.
Circulation
; 137(12): 1270-1277, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29222138
5.
Aldose reductase-mediated phosphorylation of p53 leads to mitochondrial dysfunction and damage in diabetic platelets.
Circulation
; 129(15): 1598-609, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24474649
6.
Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development.
Circ Res
; 113(1): 22-31, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23603510
7.
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.
Nat Commun
; 15(1): 275, 2024 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177131
8.
Biased suppression of TP homodimerization and signaling through disruption of a TM GxxxGxxxL helical interaction motif.
J Lipid Res
; 54(6): 1678-1690, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23493750
9.
An eicosanoid-centric view of atherothrombotic risk factors.
Cell Mol Life Sci
; 69(20): 3361-80, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22491820
10.
Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase.
ACS Med Chem Lett
; 14(12): 1631-1639, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38116426
11.
Comprehensive biochemical analysis of rare prostacyclin receptor variants: study of association of signaling with coronary artery obstruction.
J Biol Chem
; 286(9): 7060-9, 2011 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21189259
12.
A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes.
Cell Chem Biol
; 29(1): 57-66.e6, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34499862
13.
BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma.
Blood Cancer J
; 12(7): 110, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35853853
14.
CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism.
Cell Chem Biol
; 28(10): 1407-1419.e6, 2021 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33794192
15.
Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition.
Circ Res
; 102(8): 986-93, 2008 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18323528
16.
Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screen.
Sci Rep
; 10(1): 20044, 2020 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33208877
17.
Conserved rhodopsin intradiscal structural motifs mediate stabilization: effects of zinc.
Biochemistry
; 48(8): 1793-800, 2009 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19206210
18.
Prostacyclin receptor/thromboxane receptor interactions and cellular responses in human atherothrombotic disease.
Curr Atheroscler Rep
; 11(3): 227-35, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19361355
19.
Arginine (CGC) codon targeting in the human prostacyclin receptor gene (PTGIR) and G-protein coupled receptors (GPCR).
Gene
; 396(1): 180-7, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17481829
20.
Human prostacyclin receptor structure and function from naturally-occurring and synthetic mutations.
Prostaglandins Other Lipid Mediat
; 82(1-4): 95-108, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17164137