Detalhe da pesquisa
1.
Intracellular spatially-targeted chemical chaperones increase native state stability of mutant SOD1 barrel.
Biol Chem
; 404(10): 909-930, 2023 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37555646
2.
Superoxide Dismutase 1 Folding Stability as a Target for Molecular Tweezers in SOD1-Related Amyotrophic Lateral Sclerosis.
Chembiochem
; 23(21): e202200396, 2022 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36083789
3.
Effects of in vivo conditions on amyloid aggregation.
Chem Soc Rev
; 48(14): 3946-3996, 2019 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31192324
4.
Stability Effect of Quinary Interactions Reversed by Single Point Mutations.
J Am Chem Soc
; 141(11): 4660-4669, 2019 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30740972
5.
Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01.
J Am Chem Soc
; 139(16): 5640-5643, 2017 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28406616
6.
Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells.
Phys Chem Chem Phys
; 19(17): 10738-10747, 2017 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28094373
7.
The macromolecular crowding effect--from in vitro into the cell.
Biol Chem
; 397(1): 37-44, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26351910
8.
RNA Hairpin Folding in the Crowded Cell.
Angew Chem Int Ed Engl
; 55(9): 3224-8, 2016 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26833452
9.
Excluded-volume effects in living cells.
Angew Chem Int Ed Engl
; 54(8): 2548-51, 2015 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25557778
10.
Optimizing the Cell Painting assay for image-based profiling.
Nat Protoc
; 18(7): 1981-2013, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37344608
11.
Cellular ATP Levels Determine the Stability of a Nucleotide Kinase.
Front Mol Biosci
; 8: 790304, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34966785
12.
The Unfolding Journey of Superoxide Dismutase 1 Barrels under Crowding: Atomistic Simulations Shed Light on Intermediate States and Their Interactions with Crowders.
J Phys Chem Lett
; 11(10): 4206-4212, 2020 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32364389
13.
Protein Folding Modulation in Cells Subject to Differentiation and Stress.
Front Mol Biosci
; 6: 38, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31179287
14.
Role of Electrostatics in Protein-RNA Binding: The Global vs the Local Energy Landscape.
J Phys Chem B
; 121(36): 8437-8446, 2017 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28806086
15.
Imperfect crowding adaptation of mammalian cells towards osmotic stress and its modulation by osmolytes.
Mol Biosyst
; 13(11): 2218-2221, 2017 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28929156