Profiling Cycling Trauma throughout the Body with and Without Helmet Usage in a Large United States Health-care Network.

BACKGROUND: This study aimed to characterize bodily injury patterns associated with helmet usage by comparing trauma sustained by helmeted and helmetless cyclists admitted to a large US health-care system. MATERIALS AND METHODS: A prospective trauma registry associated with a large regional United States health-care network was queried for bicycle injuries resulting in hospital admission over a 5-year period. Data pertaining to helmet usage, demographics, injury description (s), Abbreviated Injury Scale score, Injury Severity Score, and hospital length of stay were collected from 140 patients treated for bicycle-related injuries. Mann-Whitney tests were performed. RESULTS: Fifty-six of the injured cyclists were helmeted (40%) and 84 were not helmeted (60%). A significantly greater proportion of helmeted cyclists exhibited abrasions and a higher incidence of injury across all injury types (P = <0.001 and 0.003). The number and severity of injury to the external body (P = <0.001 and 0.001) and overall injury severity (P = 0.004) for patients with multiple injuries were also significantly greater among helmeted cyclists. Helmeted cyclists did demonstrate significantly shorter hospital stays (P = 0.021). CONCLUSION: While the helmeted and helmetless riders admitted to the emergency department exhibit few differences in injury patterns, when significant injury differences were detected, they were more prevalent in helmeted riders. These differences were represented by minor-to-moderate injuries relative to morbidity and mortality, suggesting that the trauma profile of the helmeted and helmetless riders is relatively comparable. Yet, helmetless wearers did have significantly longer hospital stays, which may indicate underlying health disparities and/or behavioral differences.

Improved Intraoperative Communication after Utilization of Navigational Grids during Laparoscopic Cholecystectomies.

Efficient intraoperative communication (IC) between an attending and resident during surgery is highly valuable. Few tools, however, have been developed to improve IC. This study evaluates IC between residents and attendings after utilization of a navigational grid (NG) during laparoscopic cholecystectomies. Attendings and surgery residents completed a 10-question survey after performing a laparoscopic cholecystectomy. Surveys were collected for 12 weeks: six weeks before use of NGs and six weeks with use of NGs. The NGs were constructed to fit our 26-surgical monitors and allowed the monitors to be divided into a 7 × 4 grid. Hunderd and fifteen surveys were collected: 50 from attendings (pre-NG: 31 vs NG: 19) and 65 from residents (42 vs 23). Before NGs, attendings were less likely than residents to perceive attending instructions to be clear (64.5 vs 93.0%, P = 0.0001) and less likely to believe IC left little room for confusion during the procedure (64.5 vs 90.5%, P = 0.007). After NGs, attendings believed intraoperative directional guidance was more concise and clear (64.5 vs 89.5%, P = 0.062); they also reported that NGs left little room for IC confusion during the procedure (64.5 vs 94.7%, P = 0.039). Surveys showed the grid's utility to be inversely correlated with years of experience. Residents (

Histopathologic Characterization of the Expression of Vascular Endothelial Growth Factor in a Case of Retinopathy of Prematurity Treated With Ranibizumab.

PURPOSE: To characterize the expression of vascular endothelial growth factor (VEGF) in a patient with retinopathy of prematurity (ROP) treated with ranibizumab (Case 1) and compare it with a case of ROP without treatment (Case 2), a case of a premature baby without ROP (Case 3), and a case of a baby without history of ROP or prematurity (Case 4). DESIGN: Observational case series. METHODS: The eyes of the deceased babies were removed postmortem and were sent to the Florida Lions Ocular Pathology Laboratory, where they were processed. The specimens were immunostained using an antibody against VEGF. RESULTS: All eyes except for the eyes in Case 4 disclosed positive VEGF staining. Positive staining was present within the nerve fiber layer, inner plexiform layer, and inner and outer nuclear layers and within the spindle-shaped cell population in the vanguard in Case 1. In the posterior pole, positive staining was only observed at the level of the nerve fiber layer. This case also demonstrated less positive staining when compared with Case 2, where positive staining was found within all layers of the retina. CONCLUSION: Less VEGF staining was observed within the retina of the eyes treated with ranibizumab when compared with the VEGF staining in Case 2. This supports the idea that anti-VEGF agents are effective in reducing the amount of VEGF present in the retina. Furthermore, the fact that some expression of VEGF remains in the immature retina after injection supports the idea that anti-VEGF agents can suppress uncontrolled neovascularization without completely blocking the vascular drive for the vascularization of the immature retina.