Detalhe da pesquisa
1.
Selection-free precise gene repair using high-capacity adenovector delivery of advanced prime editing systems rescues dystrophin synthesis in DMD muscle cells.
Nucleic Acids Res
; 52(5): 2740-2757, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38321963
2.
Precise homology-directed installation of large genomic edits in human cells with cleaving and nicking high-specificity Cas9 variants.
Nucleic Acids Res
; 51(7): 3465-3484, 2023 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36928106
3.
Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells.
Nucleic Acids Res
; 50(13): 7761-7782, 2022 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35776127
4.
Broadening the reach and investigating the potential of prime editors through fully viral gene-deleted adenoviral vector delivery.
Nucleic Acids Res
; 49(20): 11986-12001, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34669958
5.
Precise and broad scope genome editing based on high-specificity Cas9 nickases.
Nucleic Acids Res
; 49(2): 1173-1198, 2021 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33398349
6.
Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking.
Nucleic Acids Res
; 48(2): 974-995, 2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31799604
7.
A primer to gene therapy: Progress, prospects, and problems.
J Inherit Metab Dis
; 44(1): 54-71, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32510617
8.
Integrating gene delivery and gene-editing technologies by adenoviral vector transfer of optimized CRISPR-Cas9 components.
Gene Ther
; 27(5): 209-225, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31900423
9.
Intronic SMCHD1 variants in FSHD: testing the potential for CRISPR-Cas9 genome editing.
J Med Genet
; 56(12): 828-837, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31676591
10.
Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations.
Nucleic Acids Res
; 44(3): 1449-70, 2016 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26762977
11.
Probing the impact of chromatin conformation on genome editing tools.
Nucleic Acids Res
; 44(13): 6482-92, 2016 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27280977
12.
Adenoviral vector DNA for accurate genome editing with engineered nucleases.
Nat Methods
; 11(10): 1051-7, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25152084
13.
Engineered Viruses as Genome Editing Devices.
Mol Ther
; 24(3): 447-57, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26336974
14.
Construction and characterization of adenoviral vectors for the delivery of TALENs into human cells.
Methods
; 69(2): 179-87, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24561826
15.
Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.
Nucleic Acids Res
; 41(5): e63, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23275534
16.
Nonspaced inverted DNA repeats are preferential targets for homology-directed gene repair in mammalian cells.
Nucleic Acids Res
; 40(5): 1984-99, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22080552
17.
Concerted nicking of donor and chromosomal acceptor DNA promotes homology-directed gene targeting in human cells.
Nucleic Acids Res
; 40(8): 3443-55, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22189101
18.
Development of an AdEasy-based system to produce first- and second-generation adenoviral vectors with tropism for CAR- or CD46-positive cells.
J Gene Med
; 15(1): 1-11, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23225636
19.
High-capacity adenovector delivery of forced CRISPR-Cas9 heterodimers fosters precise chromosomal deletions in human cells.
Mol Ther Nucleic Acids
; 31: 746-762, 2023 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36937620
20.
Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay.
Cell Rep Methods
; 3(6): 100488, 2023 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37426764