Caregiver's distress related to the patient's neuropsychiatric symptoms as a function of the care-setting.

Prevalence of neuropsychiatric symptoms (NPS) and correlation between its intensity and caregiver distress were evaluated as a function of the care-setting in a cross-sectional study including 72 patient-caregiver dyads. The Neuropsychiatric Inventory and the Caregiver Distress Scale were administered. The most prevalent symptoms were: in the formal care-setting, agitation/aggression and depression/dysphoria (42.4%), and in the informal care-setting, aberrant motor behavior (59.0%). While changes in appetite and eating behaviors, depression/dysphoria and irritability/lability were more prevalent in the formal care-setting (p < .0001, p = .011, p = .021), aberrant motor behavior was more prevalent in the informal care-setting (p = .007). NPS were positively correlated with caregiver distress. High patients' scores in hallucinations, sleep and night-time disturbances, anxiety, and aberrant motor behavior were the best predictors of professional caregiver's distress. Agitation/aggression, delusions, disinhibition, apathy/indifference, depression/dysphoria, and elation/euphoria were the best predictors of informal caregiver's distress. Findings may have important clinical implications.

Risk Factors of High Burden Caregivers of Dementia Patients Institutionalized at Day-Care Centres.

We examined which variables are associated with day care centres utilization among caregivers of dementia patients. A cross-sectional analysis of socio-demographic variables, relationship with caring and psychological aspects was conducted in 58 informal caregivers with intense burden. 58.6 % used day care assistance and 41.4 % did not. The results showed the importance of the commitment between the caregiver and their family and friends. The use of day care services is independent of the age, gender, educational level, marital status, occupation and relationship with the patient. However, in the multivariate analysis the provision of help by families and friends predicted the use of day care assistance. The bivariate analysis showed a significant relationship between depressive symptoms and self-rated health with day care attendance. Screening the help provision from families and friends in caregivers of dementia patients with intense burden would be relevant to design interventions which delay their institutionalization and reduce costs.

Bright Light Therapy in Older Adults with Moderate to Very Severe Dementia: Immediate Effects on Behavior, Mood, and Physiological Parameters.

Bright light therapy (BLT) has demonstrated positive short- and long-term effects in people with cognitive impairment or dementia; however, the immediate impact of BLT sessions has been scarcely investigated. In this study, we aimed to explore the immediate effects of BLT on behavior, mood, and physiological parameters (oxygen saturation/heart rate) in a sample of institutionalized older adults with moderate to very severe dementia, with a median age of 85.0 (interquartile range, IQR, 82.0-90.0), being higher in men (87.0 years, IQR 80.0-94.0) than in women (84.5 years, IQR 82.0-89.5). The BLT protocol consisted of 30-min morning sessions of 10,000 lux, Monday through Friday, for 4 weeks. The physiological parameters were recorded immediately before and after each session by pulse oximetry. Mood and behavior were assessed before, after, and during the sessions using the Interact scale. Post-session Interact scores showed a significant decrease in the items Tearful/sad and Talked spontaneously, and a significant increase in the items Enjoying self, active or alert, and Relaxed, content or sleeping appropriately. Interact scores during the sessions reflected a significant decrease in the speech-related items. Both physiological parameters changed positively from before to after sessions. Our results suggest that BLT provides immediate positive effects on mood, stimulation level, and physiological parameters, as well as a trend toward decreased speech. More robust research is needed to further explore the immediate impact of BLT. This study is registered with Clinicaltrials.gov (NCT04949984).

[Accesibility and usability of computer-based cognitive stimulation: Telecognitio]. / Accesibilidad y usabilidad de las aplicaciones computarizadas de estimulación cognitiva: Telecognitio.

INTRODUCTION: Despite of the huge technological advance in the field of computer-based cognitive interventions, very few applications have been designed to be used by the elderly. The main objective of this study was to assess the adaptability of two psycho-stimulation applications used in geriatrics. A further aim was to design a table of the minimum requirements to be met through the use of these applications in a small sample of elders. In addition, Telecognitio-an application with some interesting functionalities-is presented. MATERIAL AND METHODS: We performed a pilot test of two cognitive intervention tools, which were evaluated by a sample of elderly people through a specifically designed questionnaire. A descriptive study of the results was performed, as well as of the possible correspondence between the subjects' cognitive status and the results. RESULTS: The results of this study indicate that, in general, elderly people and especially those with cognitive impairment had difficulties in understanding the instructions for the various activities, as well as little time to answer the questions. In the case of a touch screen, errors occurred, both due to accuracy and pulse time, although this device is more intuitive than the conventional mouse. CONCLUSIONS: Computer-based cognitive stimulation and evaluation applications will become widely used among the elderly. Therefore, these applications should be adapted for universal accessibility and usability.

Prevalence of cognitive impairment: effects of level of education, age, sex and associated factors.

AIMS: To examine the prevalence of cognitive impairment in a Spanish elderly population and to analyse its association with some social and medical factors. METHODS: We randomly selected a representative sample (n = 600) of people over 65 from Narón Council (A Coruña). Socio-demographic and biomedical data were collected and cognitive status was assessed using the Mini-Mental State Examination (MMSE). RESULTS: We determined variations in the prevalence from 35.2%, when age or level of education distribution was not applied, to 22.2% when they were applied. Women showed a higher probability of cognitive impairment than men. Negative correlation was observed between the age of the subject and the MMSE score (Spearman correlation rho = -0.45, p < 0.001), with the possibility of developing cognitive impairment increasing each year. For our sample, cognitive impairment was associated with an increase of morbidity and mortality in the elderly population. This association was found with the presence of dementia, heart failure, anaemia, stroke and auditory deficits. CONCLUSIONS: Knowledge of the real prevalence rates, together with the establishment of adequate preventive and intervention measures, can be factors that may diminish the socio-sanitary impact of cognitive impairment.

Multisensory Stimulation and Individualized Music Sessions on Older Adults with Severe Dementia: Effects on Mood, Behavior, and Biomedical Parameters.

BACKGROUND: Multisensory stimulation and individualized music have shown to be good in handling the psychological and behavioral symptoms in people with severe dementia. OBJECTIVE: Explore the effects of two nonpharmacological interventions, multisensory stimulation environment (MSSE) in a Snoezelen room and individualized music sessions, on mood, behavior, and biomedical parameters of institutionalized elderly patients with severe dementia. METHODS: Randomized trial of 21 patients aged ≥65 years randomly assigned to two groups (MSSE and individualized music). Interventions administered in two-weekly sessions lasted 30 minutes for a period of 12 weeks. Main outcomes were recorded before, during, and at the end of the intervention. RESULTS: Both groups had immediate positive effects on mood and behavior. Participants were more happy/more content (p < 0.001), talked more spontaneously (p = 0.009), related to people better (p = 0.002), were more attentive to/focused on their environment (p < 0.001), enjoyed themselves (p = 0.003), were less bored/inactive (p = 0.004), and more relaxed/content (p = 0.003). The MSSE group performed a better visual follow-up of the stimuli (p = 0.044), and the music group were more relaxed and happy (p = 0.003). A decrease in heart rate (p = 0.013) and an increase in oxygen saturation (p = 0.011) were observed from before to after interventions in both groups, with no significant differences between them. CONCLUSIONS: Both interventions seem to be effective at managing mood and behavioral disturbances in the short term and at improving physiological rates, highlighting the efficacy of nonpharmacological treatments in patients with severe dementia.

Optimal nonpharmacological management of agitation in Alzheimer's disease: challenges and solutions.

Many patients with Alzheimer's disease will develop agitation at later stages of the disease, which constitutes one of the most challenging and distressing aspects of dementia. Recently, nonpharmacological therapies have become increasingly popular and have been proven to be effective in managing the behavioral symptoms (including agitation) that are common in the middle or later stages of dementia. These therapies seem to be a good alternative to pharmacological treatment to avoid unpleasant side effects. We present a systematic review of randomized controlled trials (RCTs) focused on the nonpharmacological management of agitation in Alzheimer's disease (AD) patients aged 65 years and above. Of the 754 studies found, eight met the inclusion criteria. This review suggests that music therapy is optimal for the management of agitation in institutionalized patients with moderately severe and severe AD, particularly when the intervention includes individualized and interactive music. Bright light therapy has little and possibly no clinically significant effects with respect to observational ratings of agitation but decreases caregiver ratings of physical and verbal agitation. Therapeutic touch is effective for reducing physical nonaggressive behaviors but is not superior to simulated therapeutic touch or usual care for reducing physically aggressive and verbally agitated behaviors. Melissa oil aromatherapy and behavioral management techniques are not superior to placebo or pharmacological therapies for managing agitation in AD. Further research in clinical trials is required to confirm the effectiveness and long-term effects of nonpharmacological interventions for managing agitation in AD. These types of studies may lead to the development of future intervention protocols to improve the well-being and daily functioning of these patients, thereby avoiding residential care placement.

[An exploratory study on the use of cognitive and neuropsychological assessessments in centres for the elderly in Galicia]. / Estudio exploratorio sobre el uso de instrumentos de evaluación cognitiva y neuropsicológica en centros de personas mayores de Galicia.

INTRODUCTION: Cognitive assessment is a fundamental tool in centres for the elderly when planning individualized care and intervention. The Galician Society of Gerontology and Geriatrics (Sociedade Galega of Xerontoloxía and Xeriatría) has formed a Working Group on Cognitive and Neuropsychological Assessment, with the aim of studying the tools used and to identify the main challenges in this area. MATERIAL AND METHODS: An exploratory study was conducted via an online questionnaire with Sociedade Galega of Xerontoloxía and Xeriatría members between December 2013 and January 2014. It was completed by 49 professionals, of whom 26 were professionals in psychology and 10 medical doctors. RESULTS: Consensus was found on the use of the MMSE as a screening tool, as well as the Global Deterioration Scale for dementia. There is a wide variation in the choice of general batteries of tests for the assessment of dementia (CAMCOG-R, ADAS-Cog, abbreviated Barcelona Test), and of the use of specific tests and a severe impairment battery. CONCLUSIONS: The risk of bias in the sector is suggested, with a high percentage of general practitioners using a few tools, and a small percentage using a large number of specific tools. The need for a consensus is stressed in order to facilitate assessment, objectify training needs, maximize the relationship between assessment and cognitive intervention, and provide tools to assess change.

Effects of Multisensory Stimulation on a Sample of Institutionalized Elderly People With Dementia Diagnosis: A Controlled Longitudinal Trial.

Long-term effects of multisensory stimulation were assessed using a "Snoezelen" room on older residents with dementia. Thirty patients were randomly assigned to 3 groups: multisensory stimulation environment (MSSE) group, individualized activities (activity) group, and control group. The MSSE and activity groups participated in two 30-minute weekly individualized intervention sessions over 16 weeks. Pre-, mid-, posttrial, and 8-week follow-up behavior, mood, cognitive, and functional impairment in basic activities of daily living were registered. Items included in the physically nonaggressive behavior factor improved significantly in post- versus pretrial in the MSSE group compared to the activity group, with no significant differences between MSSE and control groups. The MSSE and activity groups demonstrated behavior improvements and higher scores on the Cohen-Mansfield agitation inventory, verbal agitated behavior factor, and Neuropsychiatric Inventory-Nursing Home, with no significant differences between groups. The MSSE could have long-term positive effects on such neuropsychiatric symptoms in older people with dementia.

Multisensory stimulation on mood, behavior, and biomedical parameters in people with dementia: is it more effective than conventional one-to-one stimulation?

The purpose of this study was to assess the effects of multisensory stimulation in a multisensory stimulation environment (MSSE) such as a Snoezelen room versus one-to-one activity sessions with regard to mood, behavior, and biomedical parameters (heart rate and blood oxygen saturation). The MSSE group and activity group (one-to-one activities) of patients with dementia participated in 2 weekly individualized intervention sessions over 16 weeks, where mood and behavior before, during, and after the sessions, and biomedical parameters immediately before and after, were recorded. Immediately after the sessions, patients spoke more spontaneously, related better to others, were more attentive to their environments, more active/alert, less bored/inactive, and more relaxed/content. Both groups exhibited decreases in heart rate and increases in oxygen saturation (Spo 2) values from before to after the sessions. The MSSE sessions in a Snoezelen room were found to be as effective as activity sessions, highlighting the importance of the one-to-one interaction with the therapist.

The influence of neuroticism and extraversion on the perceived burden of dementia caregivers: an exploratory study.

Most studies reflect dementia caregivers usually sustain higher levels of burden compared to other caregivers. However, they do not consider variability within the caregiver, such as personality traits. The purpose of this study was to examine the influence of extraversion and neuroticism on dementia caregiver burden. A cross-sectional descriptive study was conducted with 33 caregivers looking after demented-patients. All caregivers had intense burden levels, and their personality, depression, anxiety and self-rated health were evaluated. Personality variables had important effects on the caregiver burden and consequences on their mental health. Neuroticism was significantly correlated with burden (r=0.6, p<0.01), depression (r=0.68, p<0.01) and both anxiety measures, state (r=0.46, p<0.01) and trait (r=0.67, p<0.01). Extraversion was significantly correlated with neuroticism (r=-0.42, p<0.01) and burden (r=-0.46, p<0.01). Finally, depression was significantly correlated with state (r=0.63, p<0.01) and trait anxiety (r=0.66, p<0.01). These results indicate the importance of considering the caregiver personality in the theoretical and empirical models of the caring process. It is necessary to adequately assess the caregiver personality, as those presenting high levels of neuroticism and low levels of extraversion are more vulnerable to experience negative caring effects.

Prevalence of functional disability in activities of daily living (ADL), instrumental activities of daily living (IADL) and associated factors, as predictors of morbidity and mortality.

The aim of this study is to establish the existing relationship among variables referred to the person, specifically age and gender, and the functional dependence in basic ADL and in IADL, as well as the possible relationship it has with the increase of morbidity and mortality in a random sample of 598 individuals older than 65 years. Of these individuals, 34.6% were categorized as dependent for at least one ADL, and 53.5% if we refer to IADL. Regarding the ADL, the risk of dependence increases (odds ratio=OR=1.089) per year of age, (OR=2.48) in women's case; while there is an IADL correlation between age and the score (r=-0.527; p<0.001). A relationship exists between dependence and the days of hospitalization (for ADL: r=-0.12, p=0.018 and IADL: r=-0.97, p=0.003), the number of visits to the doctor (ADL: r=-0.27, p<0.001; IADL: r=-0.25, p<0.001) or the presence of concomitant pathologies such as dementia (ADL: p<0.001; IADL: p<0.001). There is a significant association between age, gender and dependence, as well as between dependence and morbidity and mortality, so that dependence could be used as a predictor of both.

Estudio exploratorio sobre el uso de instrumentos de evaluación cognitiva y neuropsicológica en centros de personas mayores de Galicia / An exploratory study on the use of cognitive and neuropsychological assessessments in centres for the elderly in Galicia

Introducción: La evaluación cognitiva es una herramienta fundamental en los centros de mayores a la hora de planificar la atención e individualizar la intervención. La Sociedade Galega de Xerontoloxía e Xeriatría ha constituido un Grupo de Trabajo sobre Evaluación Cognitiva y Neuropsicológica con el objetivo de estudiar los instrumentos empleados e identificar los principales retos en esta área. Material y métodos: Se realizó un estudio exploratorio a través de encuesta en línea a los socios de la Sociedade Galega de Xerontoloxía e Xeriatría entre diciembre de 2013 y enero de 2014. Participaron 49 profesionales, de los cuales 26 eran profesionales de la psicología y 10 de la medicina. Resultados: Se encuentra un consenso en el uso del MMSE como instrumento de cribado y del GDS como escala global de la demencia. Existe mayor variabilidad en las baterías generales para la valoración de las demencias (CAMCOG-R, ADAS-Cog, Test Barcelona abreviado) y en el uso de pruebas específicas y de baterías de deterioro severo. Conclusiones: Se sugiere un riesgo de polarización del sector, en el que un porcentaje elevado de profesionales emplearía unos pocos instrumentos generales y un porcentaje pequeño un número elevado de instrumentos específicos. Se subraya la necesidad de un consenso que facilite el desempeño, objetive las necesidades formativas, maximice la relación entre evaluación e intervención cognitiva y proporcione herramientas para valorar el cambio (AU)

Introduction: Cognitive assessment is a fundamental tool in centres for the elderly when planning individualized care and intervention. The Galician Society of Gerontology and Geriatrics (Sociedade Galega of Xerontoloxía and Xeriatría) has formed a Working Group on Cognitive and Neuropsychological Assessment, with the aim of studying the tools used and to identify the main challenges in this area. Material and methods: An exploratory study was conducted via an online questionnaire with Sociedade Galega of Xerontoloxía and Xeriatría members between December 2013 and January 2014. It was completed by 49 professionals, of whom 26 were professionals in psychology and 10 medical doctors. Results: Consensus was found on the use of the MMSE as a screening tool, as well as the Global Deterioration Scale for dementia. There is a wide variation in the choice of general batteries of tests for the assessment of dementia (CAMCOG-R, ADAS-Cog, abbreviated Barcelona Test), and of the use of specific tests and a severe impairment battery. Conclusions: The risk of bias in the sector is suggested, with a high percentage of general practitioners using a few tools, and a small percentage using a large number of specific tools. The need for a consensus is stressed in order to facilitate assessment, objectify training needs, maximize the relationship between assessment and cognitive intervention, and provide tools to assess change (AU)

Accesibilidad y usabilidad de las aplicaciones computarizadas de estimulación cognitiva: Telecognitio® / Accesibility and usability of computer-based cognitive stimulation: Telecognitio®

IntroducciónEl objetivo principal de este trabajo es realizar una aproximación al grado de adaptación de dos aplicaciones de psicoestimulación utilizadas en nuestro medio. Así mismo, a través de la observación de los problemas de uso de estas dos aplicaciones uso en una pequeña muestra de personas mayores, se elabora una tabla de requisitos mínimos que a nuestro juicio deberían cumplir. Finalmente, se presenta Telecognitio®, una aplicación para la estimulación cognitiva de los mayores que incorpora ciertas funcionalidades de interés.Material y métodosSe evalúa el uso de dos herramientas de intervención cognitiva sobre una muestra de sujetos mayores a través de un cuestionario elaborado al efecto. Se realiza un análisis descriptivo de los resultados obtenidos y se sugieren posibles relaciones entre los resultados y el nivel cognitivo del sujeto.ResultadosObservamos que las personas mayores, especialmente si tienen deterioro cognitivo, presentan dificultades en la comprensión de los enunciados que transmiten las instrucciones para las diferentes actividades. Así mismo, el tiempo para responder a las cuestiones planteadas parece ser insuficiente. Cuando la pantalla es táctil se producen errores, tanto de precisión como de mantenimiento de la presión, aunque el uso de este dispositivo resulte más intuitivo que el ratón convencional.ConclusionesLas aplicaciones computarizadas de valoración y estimulación cognitiva van a constituirse en herramientas de uso generalizado entre la población de personas mayores, por lo que sería conveniente adaptarlas mejorando su accesibilidad y usabilidad(AU)

IntroductionDespite of the huge technological advance in the field of computer-based cognitive interventions, very few applications have been designed to be used by the elderly.IntroductionThe main objective of this study was to assess the adaptability of two psycho-stimulation applications used in geriatrics. A further aim was to design a table of the minimum requirements to be met through the use of these applications in a small sample of elders. In addition, Telecognitio®—an application with some interesting functionalities—is presented.Material and methodsWe performed a pilot test of two cognitive intervention tools, which were evaluated by a sample of elderly people through a specifically designed questionnaire. A descriptive study of the results was performed, as well as of the possible correspondence between the subjects’ cognitive status and the results.ResultsThe results of this study indicate that, in general, elderly people and especially those with cognitive impairment had difficulties in understanding the instructions for the various activities, as well as little time to answer the questions. In the case of a touch screen, errors occurred, both due to accuracy and pulse time, although this device is more intuitive than the conventional mouse.ConclusionsComputer-based cognitive stimulation and evaluation applications will become widely used among the elderly. Therefore, these applications should be adapted for universal accessibility and usability(AU)

Evaluación de los instrumentos WAIS-III vs. WISC-R en una muestra de personas con discapacidad intelectual en proceso de envejecimiento: estudio preliminar / No disponible

Fundamentos: El incremento de la esperanza de vida en las personas con Discapacidad Intelectual (DI) aumenta el riesgo de padecer demencia, haciéndose imprescindible la necesidad de contar con una herramienta que permita evaluar de manera fiable el grado de DI. Por lo tanto, es importante determinar cuál de las escalas de inteligencia existentes es la más apropiada para establecer el grado de discapacidad. Este trabajo pretende responder parcialmente a esta pregunta comparando los resultados obtenidos con dos de las escalas más utilizadas, el WAIS-III y el WISC-R. Métodos: Se administraron el WAIS-III y el WISC-R a 15 sujetos con DI leve o moderada en proceso de envejecimiento. Resultados: En general, las puntuaciones obtenidas en el WAIS-III fueron mayores que las del WISC-R. La correlación fue significativa en la mayoría de los subtests comunes y en los coeficientes de inteligencia verbal, manipulativo y total. El análisis de regresión mostró una gran dispersión de los datos, excepto para las puntuaciones más bajas. Conclusiones: El WAIS-III parece ser un instrumento más fiable que el WISC-R para evaluar el nivel de DI en personas en proceso de envejecimiento ya que evita el efecto suelo y cuenta con baremos adaptados para esta población (AU)

Background: Increase in life expectancy of people with Intellectual Disability (ID) raises the risk of dementia in this population and a reliable evaluation tool of the ID level is necessary. Therefore, is important to determine which of the existing intelligence scales is the most appropriate to establish the degree of ID. The aim of this research is to partially answer this question comparing the results obtained with through WAIS-III and WISC-R scales. Method: WAIS-III and WISC-R were administered to 15 individuals with mild or moderate ID aging process. Results: In general, WAIS-III scores were higher than WISC-R ones. Correlations showed significant relationship in most of the common subtests and in three IQs. The regression analysis showed a high data dispersion, except for the lowest scores. Conclusions: WAIS-III appears to be a better instrument than WISC-R in order to evaluatethe ID level in individuals with aging process because it avoids the floor effect and has standard norms for this population (AU)