Detalhe da pesquisa
1.
The next steps for genomic medicine: challenges and opportunities for the developing world.
Nat Rev Genet
; 9 Suppl 1: S23-7, 2008 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18802418
2.
A precision medicine framework using artificial intelligence for the identification and confirmation of genomic biomarkers of response to an Alzheimer's disease therapy: Analysis of the blarcamesine (ANAVEX2-73) Phase 2a clinical study.
Alzheimers Dement (N Y)
; 6(1): e12013, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32318621
3.
Evaluation of DNA microarray results with quantitative gene expression platforms.
Nat Biotechnol
; 24(9): 1115-22, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16964225
4.
Rat toxicogenomic study reveals analytical consistency across microarray platforms.
Nat Biotechnol
; 24(9): 1162-9, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17061323
5.
The Labyrinth of Product Development and Regulatory Approvals in Liquid Biopsy Diagnostics.
Clin Transl Sci
; 12(5): 431-439, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31162800
6.
The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies.
BMC Bioinformatics
; 9 Suppl 9: S10, 2008 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18793455
7.
Qualification of biomarkers for drug development in organ transplantation.
Am J Transplant
; 8(2): 267-70, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18093264
8.
The first RSBI (ISA-TAB) workshop: "can a simple format work for complex studies?".
OMICS
; 12(2): 143-9, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18447634
9.
Strategic paths for biomarker qualification.
Toxicology
; 245(3): 219-23, 2008 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18280028
10.
Histopathology of vascular injury in Sprague-Dawley rats treated with phosphodiesterase IV inhibitor SCH 351591 or SCH 534385.
Toxicol Pathol
; 36(6): 827-39, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18776163
11.
Biomarkers in peripheral blood associated with vascular injury in Sprague-Dawley rats treated with the phosphodiesterase IV inhibitors SCH 351591 or SCH 534385.
Toxicol Pathol
; 36(6): 840-9, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18776166
12.
Regulatory landscapes for biomarkers and diagnostic tests: Qualification, approval, and role in clinical practice.
Exp Biol Med (Maywood)
; 243(3): 256-261, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29110507
13.
A robust targeted sequencing approach for low input and variable quality DNA from clinical samples.
NPJ Genom Med
; 3: 2, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29354287
14.
Implementing the U.S. FDA guidance on pharmacogenomic data submissions.
Environ Mol Mutagen
; 48(5): 354-8, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17567848
15.
Questions and answers about the Pilot Process for Biomarker Qualification at the FDA.
Drug Discov Today Technol
; 4(1): 9-11, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-24980714
16.
The Predictive Safety Testing Consortium: A synthesis of the goals, challenges and accomplishments of the Critical Path.
Drug Discov Today Technol
; 4(2): 47-50, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-24980840
17.
An integrated bioinformatics infrastructure essential for advancing pharmacogenomics and personalized medicine in the context of the FDA's Critical Path Initiative.
Drug Discov Today Technol
; 4(1): 3-8, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-24980713
18.
Process map proposal for the validation of genomic biomarkers.
Pharmacogenomics
; 7(5): 773-82, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16886901
19.
Application of pharmacogenomics in clinical pharmacology.
Toxicol Mech Methods
; 16(2-3): 89-99, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-20021001
20.
Gaining Confidence on Molecular Classification through Consensus Modeling and Validation.
Toxicol Mech Methods
; 16(2-3): 59-68, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-20020998