Detalhe da pesquisa
1.
Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes.
J Med Chem
; 66(13): 9095-9119, 2023 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37399505
2.
Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia.
Nat Commun
; 13(1): 6427, 2022 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36329007
3.
The BMP ligand Gbb gates the expression of synaptic homeostasis independent of synaptic growth control.
Neuron
; 56(1): 109-23, 2007 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-17920019
4.
Mechanisms underlying the rapid induction and sustained expression of synaptic homeostasis.
Neuron
; 52(4): 663-77, 2006 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17114050
5.
Neuronal defects in a human cellular model of 22q11.2 deletion syndrome.
Nat Med
; 26(12): 1888-1898, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32989314
6.
Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders.
J Med Chem
; 63(3): 1068-1083, 2020 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31955578
7.
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning.
Nat Neurosci
; 22(3): 374-385, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718903
8.
A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients.
Elife
; 52016 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27458797
9.
Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism.
JAMA Neurol
; 73(7): 836-845, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27159400
10.
Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome.
Cell Rep
; 7(4): 1077-1092, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24794428
11.
Single-cell optogenetic excitation drives homeostatic synaptic depression.
Neuron
; 68(3): 512-28, 2010 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21040851