Detalhe da pesquisa
1.
Novel Labdane Diterpenes-Based Synthetic Derivatives: Identification of a Bifunctional Vasodilator That Inhibits CaV1.2 and Stimulates KCa1.1 Channels.
Mar Drugs
; 20(8)2022 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36005518
2.
MC225, a Novel Probe for P-glycoprotein PET Imaging at the Blood-brain Barrier: In Vitro Cardiovascular Safety Evaluation.
J Cardiovasc Pharmacol
; 70(6): 405-410, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28877068
3.
Effects of freeze-dried red wine on cardiac function and ECG of the Langendorff-perfused rat heart.
Can J Physiol Pharmacol
; 92(2): 171-4, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24502641
4.
Traceability and authentication in agri-food production: A multivariate approach to the characterization ofthe Italian food excellence elephant garlic (Allium ampeloprasum L.), a vasoactive nutraceutical.
Food Chem
; 444: 138684, 2024 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38359701
5.
Wine Lees as Source of Antioxidant Molecules: Green Extraction Procedure and Biological Activity.
Antioxidants (Basel)
; 12(3)2023 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36978870
6.
Development of potent and selective FAAH inhibitors with improved drug-like properties as potential tools to treat neuroinflammatory conditions.
Eur J Med Chem
; 246: 114952, 2023 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36462439
7.
Effects of autologous, cross-linked erythrocytes on isolated hypoperfused rabbit heart dynamics.
Pharmacology
; 90(5-6): 274-80, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23038665
8.
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature.
Vascul Pharmacol
; 143: 106969, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35149209
9.
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability.
Eur J Med Chem
; 238: 114409, 2022 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35551034
10.
The novel potent multidrug resistance inhibitors N,N-bis(cyclohexanol)amine aryl esters are devoid of vascular effects.
Pharmacology
; 88(3-4): 137-41, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21921667
11.
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents.
ACS Chem Neurosci
; 12(9): 1716-1736, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33890763
12.
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors.
J Med Chem
; 64(14): 9960-9988, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34251197
13.
Antihypertensive, cardio- and neuro-protective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats.
PLoS One
; 15(5): e0233788, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32470081
14.
Negative chronotropism, positive inotropism and lusitropism of 3,5-di-t-butyl-4-hydroxyanisole (DTBHA) on rat heart preparations occur through reduction of RyR2 Ca2+ leak.
Biochem Pharmacol
; 155: 434-443, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30036502
15.
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues.
Eur J Med Chem
; 150: 698-718, 2018 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29571157
16.
3,5-dibenzoyl-4-(3-phenoxyphenyl)-1,4-dihydro-2,6-dimethylpyridine (DP7): a new multidrug resistance inhibitor devoid of effects on Langendorff-perfused rat heart.
Eur J Pharmacol
; 563(1-3): 160-3, 2007 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17349992
17.
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain.
J Med Chem
; 59(6): 2612-32, 2016 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26888301
18.
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles.
Naunyn Schmiedebergs Arch Pharmacol
; 368(6): 470-8, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14618297
19.
Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: synthesis, biological characterization, and behavioral studies.
J Med Chem
; 57(22): 9578-97, 2014 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25343529
20.
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling.
J Med Chem
; 55(15): 6948-67, 2012 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22783984