Pesquisa | Biblioteca Virtual em Saúde

1.

Mechano-Sensing Channel PIEZO2 Enhances Invasive Phenotype in Triple-Negative Breast Cancer.

Katsuta, Eriko; Takabe, Kazuaki; Vujcic, Marija; Gottlieb, Philip A; Dai, Tao; Mercado-Perez, Arnaldo; Beyder, Arthur; Wang, Qingfei; Opyrchal, Mateusz.

Int J Mol Sci ; 23(17)2022 Aug 31.

Artigo em Inglês | MEDLINE | ID: mdl-36077309

2.

Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cells.

Jetta, Deekshitha; Gottlieb, Philip A; Verma, Deepika; Sachs, Frederick; Hua, Susan Z.

J Cell Sci ; 132(11)2019 06 12.

Artigo em Inglês | MEDLINE | ID: mdl-31076516

3.

Amphipathic molecules modulate PIEZO1 activity.

Cox, Charles D; Gottlieb, Philip A.

Biochem Soc Trans ; 47(6): 1833-1842, 2019 12 20.

Artigo em Inglês | MEDLINE | ID: mdl-31754715

4.

Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces.

Wang, Fan; Knutson, Kaitlyn; Alcaino, Constanza; Linden, David R; Gibbons, Simon J; Kashyap, Purna; Grover, Madhusudan; Oeckler, Richard; Gottlieb, Philip A; Li, Hui Joyce; Leiter, Andrew B; Farrugia, Gianrico; Beyder, Arthur.

J Physiol ; 595(1): 79-91, 2017 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-27392819

5.

Protonation of the human PIEZO1 ion channel stabilizes inactivation.

Bae, Chilman; Sachs, Frederick; Gottlieb, Philip A.

J Biol Chem ; 290(8): 5167-5173, 2015 Feb 20.

Artigo em Inglês | MEDLINE | ID: mdl-25561736

6.

Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1.

Bae, Chilman; Gnanasambandam, Radhakrishnan; Nicolai, Chris; Sachs, Frederick; Gottlieb, Philip A.

Proc Natl Acad Sci U S A ; 110(12): E1162-8, 2013 Mar 19.

Artigo em Inglês | MEDLINE | ID: mdl-23487776

7.

Mechanosensitive TRPC1 channels promote calpain proteolysis of talin to regulate spinal axon outgrowth.

Kerstein, Patrick C; Jacques-Fricke, Bridget T; Rengifo, Juliana; Mogen, Brian J; Williams, Justin C; Gottlieb, Philip A; Sachs, Fredrick; Gomez, Timothy M.

J Neurosci ; 33(1): 273-85, 2013 Jan 02.

Artigo em Inglês | MEDLINE | ID: mdl-23283340

8.

Human PIEZO1: removing inactivation.

Bae, Chilman; Gottlieb, Philip A; Sachs, Frederick.

Biophys J ; 105(4): 880-6, 2013 Aug 20.

Artigo em Inglês | MEDLINE | ID: mdl-23972840

9.

Cell biology: The sensation of stretch.

Gottlieb, Philip A; Sachs, Frederick.

Nature ; 483(7388): 163-4, 2012 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-22398551

10.

Preface.

Gottlieb, Philip A.

Curr Top Membr ; 79: xiii-xiv, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28728826

11.

The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4.

Bae, Chilman; Sachs, Frederick; Gottlieb, Philip A.

Biochemistry ; 50(29): 6295-300, 2011 Jul 26.

Artigo em Inglês | MEDLINE | ID: mdl-21696149

12.

Effects of GsMTx4 on bacterial mechanosensitive channels in inside-out patches from giant spheroplasts.

Kamaraju, Kishore; Gottlieb, Philip A; Sachs, Frederick; Sukharev, Sergei.

Biophys J ; 99(9): 2870-8, 2010 Nov 03.

Artigo em Inglês | MEDLINE | ID: mdl-21044584

13.

A mechanosensitive ion channel regulating cell volume.

Hua, Susan Z; Gottlieb, Philip A; Heo, Jinseok; Sachs, Frederick.

Am J Physiol Cell Physiol ; 298(6): C1424-30, 2010 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-20457830

14.

Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers.

Suchyna, Thomas M; Tape, Sonya E; Koeppe, Roger E; Andersen, Olaf S; Sachs, Frederick; Gottlieb, Philip A.

Nature ; 430(6996): 235-40, 2004 Jul 08.

Artigo em Inglês | MEDLINE | ID: mdl-15241420

15.

Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters.

Ridone, Pietro; Pandzic, Elvis; Vassalli, Massimo; Cox, Charles D; Macmillan, Alexander; Gottlieb, Philip A; Martinac, Boris.

J Gen Physiol ; 152(8)2020 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-32582958

16.

The slow force response to stretch in atrial and ventricular myocardium from human heart: functional relevance and subcellular mechanisms.

Kockskämper, Jens; von Lewinski, Dirk; Khafaga, Mounir; Elgner, Andreas; Grimm, Michael; Eschenhagen, Thomas; Gottlieb, Philip A; Sachs, Frederick; Pieske, Burkert.

Prog Biophys Mol Biol ; 97(2-3): 250-67, 2008.

Artigo em Inglês | MEDLINE | ID: mdl-18466959

17.

Concentration dependent effect of GsMTx4 on mechanosensitive channels of small conductance in E. coli spheroplasts.

Hurst, Annette C; Gottlieb, Philip A; Martinac, Boris.

Eur Biophys J ; 38(4): 415-25, 2009 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-19132368

18.

Hereditary xerocytosis revisited.

Archer, Natasha M; Shmukler, Boris E; Andolfo, Immacolata; Vandorpe, David H; Gnanasambandam, Radhakrishnan; Higgins, John M; Rivera, Alicia; Fleming, Mark D; Sachs, Frederick; Gottlieb, Philip A; Iolascon, Achille; Brugnara, Carlo; Alper, Seth L; Nathan, David G.

Am J Hematol ; 89(12): 1142-6, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25044010

19.

Angiotensin II and myosin light-chain phosphorylation contribute to the stretch-induced slow force response in human atrial myocardium.

Kockskämper, Jens; Khafaga, Mounir; Grimm, Michael; Elgner, Andreas; Walther, Stefanie; Kockskämper, Anke; von Lewinski, Dirk; Post, Heiner; Grossmann, Marius; Dörge, Hilmar; Gottlieb, Philip A; Sachs, Frederick; Eschenhagen, Thomas; Schöndube, Friedrich A; Pieske, Burkert.

Cardiovasc Res ; 79(4): 642-51, 2008 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-18503051

20.

Functional analyses of heteromeric human PIEZO1 Channels.

Gnanasambandam, Radhakrishnan; Bae, Chilman; Ziegler, Lynn; Sachs, Frederick; Gottlieb, Philip A.

PLoS One ; 13(11): e0207309, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-30462693

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