Detalhe da pesquisa
1.
One-Pot Synthesis of N-Fused Benzimidazo-ß-carbolines through Sequential Propargylation/aza-Cycloisomerization Approach.
J Org Chem
; 89(4): 2675-2682, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38319121
2.
Domino alkyne insertion/aldol reaction/aromatization of 2-alkynyl indole-3-carbaldehyde with 1,3-diketones: entry to 2-indolyl phenols.
Org Biomol Chem
; 21(5): 1046-1055, 2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36625740
3.
Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents.
Int J Mol Sci
; 24(12)2023 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37373544
4.
Discovery of potent dual ligands for dopamine D4 and σ1 receptors.
Bioorg Med Chem
; 69: 116851, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35753263
5.
Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases.
Molecules
; 27(19)2022 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36234686
6.
Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains.
Bioorg Med Chem Lett
; 52: 128390, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34601029
7.
Structural revision of the Mcl-1 inhibitor MIM1: synthesis and biological studies on ovarian cancer cells with evaluation of designed analogues.
Org Biomol Chem
; 19(41): 8968-8987, 2021 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34596646
8.
Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase.
Bioorg Med Chem
; 31: 115962, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33422908
9.
Metal-free propargylation/aza-annulation approach to substituted ß-carbolines and evaluation of their photophysical properties.
Org Biomol Chem
; 17(42): 9291-9304, 2019 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31626261
10.
Strategies towards the synthesis of anti-tuberculosis drugs.
Org Biomol Chem
; 17(22): 5428-5459, 2019 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31111850
11.
Synthesis and biological evaluation of longanlactone analogues as neurotrophic agents.
Bioorg Med Chem Lett
; 28(4): 673-676, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29402744
12.
Preparation of imidazo[1,2-a]-N-heterocyclic derivatives with gem-difluorinated side chains.
Beilstein J Org Chem
; 13: 2115-2121, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29062431
13.
α-Hydroxyallylsilanes as propionaldehyde enolate equivalents and their use toward iterative aldol reactions.
J Org Chem
; 80(4): 2364-75, 2015 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25636066
14.
A combination of in silico and SAR studies to identify binding hot spots of Bcl-xL inhibitors.
Bioorg Med Chem
; 23(8): 1747-57, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25797160
15.
Tuning the reactivity of oxygen/sulfur by acidity of the catalyst in Prins cyclization: oxa- versus thia-selectivity.
J Org Chem
; 79(6): 2716-22, 2014 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24564269
16.
Design, synthesis and biological evaluation of new inhibitors of Bax/Bcl-xL interaction in cancer cells.
Bioorg Med Chem Lett
; 24(7): 1758-61, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24602902
17.
Synergistic effects between Lewis and Brønsted acids: application to the Prins cyclization.
J Org Chem
; 78(19): 9892-7, 2013 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23984760
18.
Synthesis of enones, pyrazolines and pyrrolines with gem-difluoroalkyl side chains.
Beilstein J Org Chem
; 9: 1943-8, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24204405
19.
Acylsilane Directed Rh-Catalyzed Arene C-H Alkylation with Maleimides and Visible-Light-Induced Siloxycarbene-Amide Cyclization: [3 + 2] Carbo-Annulation in Ru Catalysis.
Org Lett
; 25(15): 2594-2599, 2023 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37036267
20.
Synthesis and neurite growth evaluation of new analogues of honokiol, a neolignan with potent neurotrophic activity.
Bioorg Med Chem Lett
; 22(3): 1439-44, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22209461