Alogia and pressured speech do not fall on a continuum of speech production using objective speech technologies.

Speech production is affected in a variety of serious mental illnesses (SMI; e.g., schizophrenia, unipolar depression, bipolar disorders) and at its extremes can be observed in the gross reduction of speech (e.g., alogia) or increase of speech (e.g., pressured speech). The present study evaluated whether clinically-rated alogia and pressured speech represent antithetical constructs when analyzed using objective metrics of speech production. We examined natural speech using acoustic and natural language processing features from two archival studies using several different speaking tasks and a combined 107 patients meeting criteria for SMI. Contrary to expectations, we did not find that alogia and pressured speech presented as opposing ends of a speech production continuum. Objective speech markers were associated with clinically rated alogia but not pressured speech, and these results were consistent across speaking tasks and studies. Implications for our understanding of speech production symptoms in SMI are discussed, as well as implications for Natural Language Processing and digital phenotyping efforts more generally.

Talking about Health: A Topic Analysis of Narratives from Individuals with Schizophrenia and Other Serious Mental Illnesses.

Individuals with schizophrenia have higher mortality and shorter lifespans. There are a multitude of factors which create these conditions, but one aspect is worse physical health, particularly cardiovascular and metabolic health. Many interventions to improve the health of individuals with schizophrenia have been created, but on the whole, there has been limited effectiveness in improving quality of life or lifespan. One potential new avenue for inquiry involves a more patient-centric perspective; understanding aspects of physical health most important, and potentially most amenable to change, for individuals based on their life narratives. This study used topic modeling, a type of Natural Language Processing (NLP) on unstructured speech samples from individuals (n = 366) with serious mental illness, primarily schizophrenia, in order to extract topics. Speech samples were drawn from three studies collected over a decade in two geographically distinct regions of the United States. Several health-related topics emerged, primarily centered around food, living situation, and lifestyle (e.g., routine, hobbies). The implications of these findings for how individuals with serious mental illness and schizophrenia think about their health, and what may be most effective for future health promotion policies and interventions, are discussed.