Detalhe da pesquisa
1.
Canadian COVID-19 host genetics cohort replicates known severity associations.
PLoS Genet
; 20(3): e1011192, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38517939
2.
Genetic architecture: the shape of the genetic contribution to human traits and disease.
Nat Rev Genet
; 19(2): 110-124, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29225335
3.
Single base-pair resolution analysis of DNA binding motif with MoMotif reveals an oncogenic function of CTCF zinc-finger 1 mutation.
Nucleic Acids Res
; 50(15): 8441-8458, 2022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35947648
4.
Examining the interaction between prenatal stress and polygenic risk for attention-deficit/hyperactivity disorder on brain growth in childhood: Findings from the DREAM BIG consortium.
Dev Psychobiol
; 66(4): e22481, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38538956
5.
A Bayesian hierarchical model for improving measurement of 5mC and 5hmC levels: Toward revealing associations between phenotypes and methylation states.
Genet Epidemiol
; 46(7): 446-462, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35753057
6.
Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models.
PLoS Genet
; 16(5): e1008766, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32365090
7.
Block coordinate descent algorithm improves variable selection and estimation in error-in-variables regression.
Genet Epidemiol
; 45(8): 874-890, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34468045
8.
An effector index to predict target genes at GWAS loci.
Hum Genet
; 141(8): 1431-1447, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35147782
9.
Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases.
Genet Med
; 24(7): 1545-1555, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35460399
10.
The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals.
Clin Proteomics
; 19(1): 34, 2022 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36171541
11.
Genome-wide analysis of gene dosage in 24,092 individuals estimates that 10,000 genes modulate cognitive ability.
Mol Psychiatry
; 26(6): 2663-2676, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33414497
12.
Combined polygenic risk scores of different psychiatric traits predict general and specific psychopathology in childhood.
J Child Psychol Psychiatry
; 63(6): 636-645, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34389974
13.
A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene.
PLoS Genet
; 15(8): e1008344, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31469826
14.
Estimating the effects of copy-number variants on intelligence using hierarchical Bayesian models.
Genet Epidemiol
; 44(8): 825-840, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32783248
15.
MDiNE: a model to estimate differential co-occurrence networks in microbiome studies.
Bioinformatics
; 36(6): 1840-1847, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697315
16.
Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening.
Genet Med
; 23(3): 508-515, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33110269
17.
A novel statistical method for modeling covariate effects in bisulfite sequencing derived measures of DNA methylation.
Biometrics
; 77(2): 424-438, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32438470
18.
The UK10K project identifies rare variants in health and disease.
Nature
; 526(7571): 82-90, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26367797
19.
Constrained instruments and their application to Mendelian randomization with pleiotropy.
Genet Epidemiol
; 43(4): 373-401, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30635941
20.
Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study.
PLoS Med
; 17(7): e1003152, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32614825