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1.
Aviakosm Ekolog Med ; 49(2): 23-31, 2015.
Artigo em Russo | MEDLINE | ID: mdl-26087583

RESUMO

Previously it has been shown that argon has a stimulating effect on biological processes including, specifically, strong protective properties during exposure to acute (1-4 hrs.) hypoxic hypoxia. Experiments with animals under hypoxia gradually growing over 3 to 7 days may give insight into mechanisms of the argon protective action. Purpose of the work was to explore character and severity of developing disorders, to attempt their prognosis and to test potentiality of argon as a protector from the effects of subacute hypoxic exposure. In two series of experiments Wistar male rats were housed in pressure chambers with different rates of O2 reduction without argon and with argon in concentration of 32-38%. Oxygen reduction from 20.9 to 9.0% in 3 days led to the death of 50% animals. Oxygen reduction to 12.0% in 7 days and one day in low-oxygen atmosphere was harmless for animals. Argon in air makes the response to hypoxia almost twice as sharp on virtually every level (red blood system, physiological, morphological and biochemical shifts) validating the concept that argon acts as a stimulator. In context of the most critical processes of adaptation to hypoxia--activation of blood formation and lipid metabolism--this sharpening of the response results in depletion of body resources and instigates irreversible shifts.


Assuntos
Adaptação Fisiológica/efeitos dos fármacos , Argônio/farmacologia , Ambiente Controlado , Hipóxia/prevenção & controle , Animais , Modelos Animais de Doenças , Seguimentos , Hipóxia/metabolismo , Hipóxia/patologia , Metabolismo dos Lipídeos/efeitos dos fármacos , Masculino , Oxigênio/metabolismo , Ratos , Ratos Wistar
2.
Voen Med Zh ; 326(4): 45-8, 96, 2005 Apr.
Artigo em Russo | MEDLINE | ID: mdl-15962601

RESUMO

According to the tasks and initiative of RF MD Main Military Medical Headquarters the series of research and experimental designers' work was performed. It allowed determining the main principles of anew conception of supplying the mobile medical formations with oxygen and creating the necessary technical means for its realization, i.e. for autonomous supply of medical service troop link with oxygen. The most optimal schemes of new technical mean application to obtain the oxygen at the stages of medical evacuation were worked out. The oxygen supply system based on the use of created technical means of its production is easily adapted to dynamically changing problems of medical service. The state trials have confirmed the prospects of the conception proposed.


Assuntos
Ambulâncias , Militares , Oxigenoterapia/instrumentação , Humanos , Federação Russa
3.
Aviakosm Ekolog Med ; 36(4): 59, 2002.
Artigo em Russo | MEDLINE | ID: mdl-12442594

RESUMO

Efficiency of different means (thermoinsulating blankets, warmers, heliox mixtures) used to eliminate hypothermia of varying degree was evaluated with a complex model of interrelated physiological systems.


Assuntos
Reanimação Cardiopulmonar/métodos , Serviços Médicos de Emergência , Hipotermia/terapia , Humanos
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