Detalhe da pesquisa
1.
Thyroid hormone receptor-ß agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways.
Am J Physiol Endocrinol Metab
; 305(1): E89-100, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23651850
2.
Sitagliptin reduces hyperglycemia and increases satiety hormone secretion more effectively when used with a novel polysaccharide in obese Zucker rats.
J Nutr
; 142(10): 1812-20, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22915295
3.
Energetic signalling in the control of mitochondrial F1F0 ATP synthase activity in health and disease.
Int J Biochem Cell Biol
; 40(12): 2698-701, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18707016
4.
Anti-obesity, anti-diabetic, and lipid lowering effects of the thyroid receptor beta subtype selective agonist KB-141.
J Steroid Biochem Mol Biol
; 111(3-5): 262-7, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18621127
5.
Pharmacological and x-ray structural characterization of a novel selective androgen receptor modulator: potent hyperanabolic stimulation of skeletal muscle with hypostimulation of prostate in rats.
Endocrinology
; 148(1): 4-12, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17008401
6.
Discovery of potent and muscle selective androgen receptor modulators through scaffold modifications.
J Med Chem
; 50(13): 3015-25, 2007 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17552509
7.
Therapeutic potential for thyroid hormone receptor-beta selective agonists for treating obesity, hyperlipidemia and diabetes.
Curr Vasc Pharmacol
; 5(2): 141-54, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17430219
8.
The isolated, perfused pseudo-working heart model.
Methods Mol Med
; 139: 145-50, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18287669
9.
Thyroid receptor ligands. 6. A high affinity "direct antagonist" selective for the thyroid hormone receptor.
J Med Chem
; 49(23): 6635-7, 2006 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17154490
10.
Discovery of potent, orally-active, and muscle-selective androgen receptor modulators based on an N-aryl-hydroxybicyclohydantoin scaffold.
J Med Chem
; 49(26): 7596-9, 2006 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17181141
11.
Reduction of skeletal muscle atrophy by a proteasome inhibitor in a rat model of denervation.
Exp Biol Med (Maywood)
; 231(3): 335-41, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16514182
12.
Cardioselective sulfonylthiourea HMR 1098 blocks mitochondrial uncoupling induced by a KATP channel opener, P-1075, in beating rat hearts.
Biochim Biophys Acta
; 1638(2): 121-8, 2003 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-12853117
13.
Sarcolemmal and mitochondrial effects of a KATP opener, P-1075, in "polarized" and "depolarized" Langendorff-perfused rat hearts.
Biochim Biophys Acta
; 1618(1): 39-50, 2003 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-14643932
14.
Effects of mitochondrial K(ATP) modulators on cardioprotection induced by chronic high altitude hypoxia in rats.
Cardiovasc Res
; 55(3): 567-75, 2002 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12160954
15.
Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: selective actions relative to 3,5,3'-triiodo-L-thyronine.
Endocrinology
; 145(4): 1656-61, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-14701670
16.
Small molecule mitochondrial F1F0 ATPase hydrolase inhibitors as cardioprotective agents. Identification of 4-(N-arylimidazole)-substituted benzopyran derivatives as selective hydrolase inhibitors.
J Med Chem
; 47(5): 1081-4, 2004 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-14971888
17.
The mitochondrial K(ATP) channel opener BMS-191095 induces neuronal preconditioning.
Neuroreport
; 15(2): 345-9, 2004 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-15076766
18.
Combining sitagliptin/metformin with a functional fiber delays diabetes progression in Zucker rats.
J Endocrinol
; 220(3): 361-73, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24389593
19.
Bacterial biosensors for screening isoform-selective ligands for human thyroid receptors α-1 and ß-1.
FEBS Open Bio
; 2: 247-53, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23667826
20.
Thyroid hormone suppression of ß-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events.
Mol Cell Endocrinol
; 339(1-2): 72-80, 2011 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21458529