Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 4 de 4
Filtrar
1.
Violence Against Women ; 30(6-7): 1383-1406, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-36862805

RESUMO

The largest European victimization survey of violence against women (VAW), has revealed an interesting paradox: countries with the highest gender equality indices had the highest VAW indices, while countries with low gender equality, also had low VAW indices. The country with the lowest VAW rates was Poland. This article attempts to explain this paradox. First, the results of the FRA study regarding Poland and its methodological issues are described. As these explanations may prove insufficient, it is necessary to recourse to sociological theories of VAW, together with analyses of the sociocultural roles of women, and gender relations since the communist period (1945-1989). The key question is whether the Polish variant of the patriarchy is more respectful toward women than Western European gender equality.


Assuntos
Estrutura Familiar , Equidade de Gênero , Humanos , Feminino , Polônia , Violência , Relações Interpessoais
2.
Development ; 135(21): 3543-53, 2008 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18832391

RESUMO

The duplication-degeneration-complementation (DDC) model predicts that subfunctionalization of duplicated genes is a common mechanism for their preservation. The additional Hox complexes of teleost fish constitute a good system in which to test this hypothesis. Zebrafish have two hoxb complexes, with two hoxb5 genes, hoxb5a and hoxb5b, the expression patterns of which suggest subfunctionalization of an ancestral hoxb5 gene. We characterized conserved non-coding elements (CNEs) near the zebrafish hoxb5 genes. One CNE, J3, is only retained in the hoxb5a locus, whereas the others, J1 and J2, are present in both hoxb5 loci. When tested individually, the enhancer activity of individual CNEs, including J3, extensively overlapped and did not support a role in subfunctionalization. By contrast, reporter transgene constructs encompassing multiple CNEs were able to target reporter gene expression to unique domains of hoxb5a and hoxb5b expression. The deletion of J3 from the hoxb5a locus resulted in expression that approached that of hoxb5b, whereas its insertion in the hoxb5b locus increased reporter expression and rendered it more similar to that of hoxb5a. Our results highlight the importance of interactions between CNEs in the execution of complementary subfunctions of duplicated genes.


Assuntos
Genes Duplicados , Proteínas de Homeodomínio/genética , Proteínas de Peixe-Zebra/genética , Peixe-Zebra/genética , Animais , Animais Geneticamente Modificados , Sítios de Ligação , Sequência Conservada , DNA Intergênico/genética , Embrião de Mamíferos/citologia , Embrião de Mamíferos/metabolismo , Embrião não Mamífero/citologia , Embrião não Mamífero/metabolismo , Elementos Facilitadores Genéticos , Regulação da Expressão Gênica no Desenvolvimento , Genes Reporter , Proteínas de Fluorescência Verde/metabolismo , Proteínas de Homeodomínio/metabolismo , Camundongos , Filogenia , Homologia de Sequência do Ácido Nucleico , Peixe-Zebra/embriologia , Proteínas de Peixe-Zebra/metabolismo , beta-Galactosidase/metabolismo
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA