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1.
Nutr Cancer ; 71(8): 1283-1289, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31058544

RESUMO

The objective was to estimate the risk of breast cancer (BC) molecular subtypes in relation to the average glycemic index (GI) and the dietary glycemic load (GL) in Mexican women. From 2007 to 2011, a study of incident cases and population controls was conducted in five states of northern Mexico. A subsample of 509 cases matched 1:1 by age with 509 controls was selected. With a food frequency questionnaire, information about diet was obtained, and GI and GL were calculated. The expression of human epidermal growth factor receptor 2 (HER2), and estrogen (ER) and progesterone (PR) receptors in tumors was obtained from medical records. Patients were classified as luminal A (RE+ and/or PR+/HER2-), HER2+ (RE+ and/or PR+/HER2+ and RE-/PR-/HER2+), or triple negative (TN) (RE-/PR-/HER2-). GI and GL associations with BC molecular subtypes were evaluated using conditional logistic regression models. GI was positively associated with luminal A (OR= 1.12; 95% CI: 1.03, 1.22), HER2+ (OR= 1.15; 95% CI: 1.02, 1.30), and TN (OR= 1.20; 95% CI: 1.03, 1.39) BC. GL was not associated with BC molecular subtypes. These results suggest that the type of carbohydrate consumed is associated with increased BC regardless of the luminal A, HER2+, and TN subtypes.


Assuntos
Biomarcadores Tumorais/metabolismo , Neoplasias da Mama/etiologia , Dieta/efeitos adversos , Índice Glicêmico , Carga Glicêmica , Adulto , Neoplasias da Mama/metabolismo , Neoplasias da Mama/patologia , Estudos de Casos e Controles , Feminino , Humanos , México , Pessoa de Meia-Idade , Receptor ErbB-2/metabolismo , Receptores de Estrogênio/metabolismo , Receptores de Progesterona/metabolismo , Estudos Retrospectivos
2.
Pediatr Blood Cancer ; 64(1): 13-17, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-27468131

RESUMO

Childhood, adolescent, and young adult cancer survivors demonstrate increased cardio-metabolic risk factors, which are amenable to lifestyle changes. The use of technology to impact lifestyle change expands previously limited intervention access, yet little is known about its use. We summarized lifestyle interventions for survivors delivered using technology, finding six studies, primarily targeting physical activity. Study samples were small and durations ranged from 5 to 16 weeks and outcomes modest. Participants were older, white, survivors of leukemia or brain tumors, and the majority received Web-based interventions. Study quality was moderate. Few technology-based interventions have been developed, suggesting an area of opportunity for survivors.


Assuntos
Terapia Comportamental , Estilo de Vida , Neoplasias/psicologia , Qualidade de Vida , Sobreviventes/psicologia , Adolescente , Adulto , Criança , Humanos , Neoplasias/prevenção & controle , Adulto Jovem
3.
Cureus ; 16(5): e61177, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38933626

RESUMO

Breastfeeding is the fundamental, physiological, and psychosocial process by which the mother feeds the newborn. Early initiation of breastfeeding is recommended within the first hour of life and exclusive breastfeeding up to six months of age due to its optimal contribution of nutrients for the development of the newborn. Despite this, there are factors that affect this process which involve the nutritional, physical, and psychological state of the mother, such as food security or food insecurity, however, it is unknown if it will have a decisive impact on these factors concerning the cessation of breastfeeding or total duration of breastfeeding. This study is an in-depth review of the available information related to food security as a determinant in breastfeeding practices. We did a scoping review between December 2022 - January 2023. The principal inclusion criteria were: the use of the English language, qualitative and quantitative methods, and analytical studies. All the articles were available in full text and the manuscripts ranged from 1997 and 2022. Twelve studies were included: eight quantitative, two qualitative, and two mixed. In the quantitative studies, significant positive and negative associations were found between food insecurity, exclusive breastfeeding, early initiation of breastfeeding, cessation of breastfeeding, and total duration of breastfeeding. For their part, qualitative and mixed studies describe that women with severe food insecurity tend to feel weak and may have a poor perception of their diet and, consequently, their breastfeeding practices are lower. Moreover, there are qualitative studies that mention that the higher the food insecurity, the more frequently breastfeeding occurs. The inconsistency in the results may be due to factors involving the characteristics of each population, the instrument used to measure food security, and the variables by which the models were adjusted. It is necessary to carry out more studies on the subject since it is obvious that the relationship between the variables needs to be clarified.

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