Detalhe da pesquisa
1.
Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.
Cell
; 162(3): 552-63, 2015 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26232225
2.
Increased demand for NAD+ relative to ATP drives aerobic glycolysis.
Mol Cell
; 81(4): 691-707.e6, 2021 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33382985
3.
Lack of Evidence for PKM2 Protein Kinase Activity.
Mol Cell
; 59(5): 850-7, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26300261
4.
Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation.
Mol Cell
; 57(1): 95-107, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25482511
5.
Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells.
Mol Cell
; 55(2): 253-63, 2014 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24882210
6.
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Nature
; 520(7547): 363-7, 2015 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25855294
7.
Antibody-mediated neutralization of perfringolysin o for intracellular protein delivery.
Mol Pharm
; 12(6): 1992-2000, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25881713
8.
Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability.
Elife
; 82019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30990168
9.
Targeting Metabolism for Cancer Therapy.
Cell Chem Biol
; 24(9): 1161-1180, 2017 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28938091
10.
Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition.
Elife
; 62017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28826492
11.
Altered metabolite levels in cancer: implications for tumour biology and cancer therapy.
Nat Rev Cancer
; 16(11): 680-693, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27658530
12.
Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.
Cell Metab
; 24(5): 716-727, 2016 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27746050
13.
Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.
Cell Metab
; 23(3): 517-28, 2016 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26853747
14.
Allosteric regulation of PKM2 allows cellular adaptation to different physiological states.
Sci Signal
; 6(263): pe7, 2013 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23423437