Detalhe da pesquisa
1.
Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation.
Proc Natl Acad Sci U S A
; 114(35): 9421-9426, 2017 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28811369
2.
Role for the obesity-related FTO gene in the cellular sensing of amino acids.
Proc Natl Acad Sci U S A
; 110(7): 2557-62, 2013 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23359686
3.
The biology of FTO: from nucleic acid demethylase to amino acid sensor.
Diabetologia
; 56(10): 2113-21, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23896822
4.
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.
Nat Genet
; 49(1): 17-26, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27841877
5.
FTO is necessary for the induction of leptin resistance by high-fat feeding.
Mol Metab
; 4(4): 287-98, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25830092
6.
Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm.
Biosci Rep
; 34(5)2014 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25242086
7.
Corrigendum: Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.
Nat Genet
; 49(2): 317, 2017 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28138151
8.
Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
Cell Metab
; 11(5): 390-401, 2010 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20444419
9.
Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.
Cell Metab
; 7(5): 456-65, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18460336
10.
Investigation of protein-tyrosine phosphatases by in-gel assays.
Methods
; 35(1): 22-7, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15588982
11.
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.
Proc Natl Acad Sci U S A
; 102(40): 14238-43, 2005 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-16176982
12.
UVA inactivates protein tyrosine phosphatases by calpain-mediated degradation.
EMBO Rep
; 5(8): 812-7, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15247926