RESUMO
Introduction: Oral adverse reactions related to natural dermal fillers may originate from infiltration techniques, giving rise to swellings, nodule formation doe to local material entrapment, or displacement or migration of the material used. Objective: describe a case of orofacial foreign body reaction in an elderly patient. Case report: a 65-year-old woman was referred for oral evaluation complaining of an intraoral lesion present for 15 days. Intraoral examination revealed a mobile nodule in the lower lip left portion. After the initial consultation, incisional biopsy was performed under local anesthesia and the surgical specimen was sent for histopathological analysis. Intraoral examination revealed a soft mobile nodule in the lower lip left portion. Clinical pathological and Raman microspectroscopy analysis led to a final diagnosis of calcium hydroxyapatite dermal filler-related reaction. Conclusions: this case reinforces the possibility of dermal filler-related mucosal tissue reactions in oral cavity soft tissues(AU)
Introducción: las reacciones adversas bucales relacionadas con rellenos dérmicos naturales pueden originarse a partir de técnicas de infiltración, lo que ocasiona inflamaciones, formación de nódulos por atrapamiento de material local o desplazamiento o migración del material usado. Objetivo: describir un caso de reacción a cuerpo extraño bucofacial en un adulto mayor. Presentación del caso: una mujer de 65 años de edad fue remitida para evaluación bucal por presentar una lesión intrabucal durante 15 días. El examen intrabucal reveló un nódulo móvil en la porción izquierda del labio inferior. Después de la consulta inicial, se realizó una biopsia incisional bajo anestesia local y se envió la muestra quirúrgica para su análisis histopatológico. El examen intrabucal reveló un nódulo móvil suave en la porción izquierda del labio inferior. El análisis clínico-patológico y de la micro-espectroscopia de Raman condujeron a un diagnóstico final de reacción de hidroxiapatita cálcica relacionada con el relleno dérmico. Conclusiones: este caso refuerza la posibilidad de reacciones cutáneas relacionadas con los rellenos dérmicos en los tejidos mucosos de la cavidad bucal(AU)
Assuntos
Humanos , Feminino , Idoso , Análise Espectral Raman/métodos , Durapatita/efeitos adversos , Preenchedores Dérmicos/efeitos adversos , Boca/lesõesRESUMO
Introduction: Oral adverse reactions related to natural dermal fillers may originate from infiltration techniques, giving rise to swellings, nodule formation doe to local material entrapment, or displacement or migration of the material used. Objective: describe a case of orofacial foreign body reaction in an elderly patient. Case report: a 65-year-old woman was referred for oral evaluation complaining of an intraoral lesion present for 15 days. Intraoral examination revealed a mobile nodule in the lower lip left portion. After the initial consultation, incisional biopsy was performed under local anesthesia and the surgical specimen was sent for histopathological analysis. Intraoral examination revealed a soft mobile nodule in the lower lip left portion. Clinical pathological and Raman microspectroscopy analysis led to a final diagnosis of calcium hydroxyapatite dermal filler-related reaction. Conclusions: this case reinforces the possibility of dermal filler-related mucosal tissue reactions in oral cavity soft tissues(AU)
Introducción: las reacciones adversas bucales relacionadas con rellenos dérmicos naturales pueden originarse a partir de técnicas de infiltración, lo que ocasiona inflamaciones, formación de nódulos por atrapamiento de material local o desplazamiento o migración del material usado. Objetivo: describir un caso de reacción a cuerpo extraño bucofacial en un adulto mayor. Presentación del caso: una mujer de 65 años de edad fue remitida para evaluación bucal por presentar una lesión intrabucal durante 15 días. El examen intrabucal reveló un nódulo móvil en la porción izquierda del labio inferior. Después de la consulta inicial, se realizó una biopsia incisional bajo anestesia local y se envió la muestra quirúrgica para su análisis histopatológico. El examen intrabucal reveló un nódulo móvil suave en la porción izquierda del labio inferior. El análisis clínico-patológico y de la micro-espectroscopia de Raman condujeron a un diagnóstico final de reacción de hidroxiapatita cálcica relacionada con el relleno dérmico. Conclusiones: este caso refuerza la posibilidad de reacciones cutáneas relacionadas con los rellenos dérmicos en los tejidos mucosos de la cavidad bucal(AU)
Assuntos
Humanos , Feminino , Idoso , Análise Espectral Raman/métodos , Durapatita/efeitos adversos , Preenchedores Dérmicos/efeitos adversos , Boca/lesõesRESUMO
BACKGROUND: This study aimed to review translational studies focusing on third molar removal surgeries through a systematic analytical approach. MATERIAL AND METHODS: A PROSPERO-registered systematic review (CRD42017060455) was conducted following the PRISMA statement to summarize current knowledge on gene expression in third molar surgeries. A search was performed in PubMed's Medline and Scopus databases, without date or language restrictions, using the logical expression {[(Third molar) OR (preemptive) OR (cyclooxygenase inhibitors) OR (acute inflammation) AND (gene expression)]}. RESULTS: All studies included in the analysis evaluated gene expression in a third molar extraction model, using the preemptive analgesia methodology in seven investigations. The sample analyzed was obtained from gingival tissue biopsy (n=4), blood (n=1), transudate (n=1) and gingival tissue biopsy/transudate (n=1). There were differences with respect to evaluated genes, drug protocol, sample studied, and method for evaluating gene expression. CONCLUSIONS: Third molar surgeries were found to be associated with different COX-related gene expression patterns. Although inflammatory events following the surgical procedure are associated with COX isoforms, data from preemptive analgesia studies are scarce, especially from studies correlating gene expression and clinical parameters. In the future, from a clinical perspective, identifying the molecular targets of a drug based on individual gene expression may be helpful to delineate specific third molar, surgery-related, preemptive analgesia protocols
Assuntos
Humanos , Dente Serotino/cirurgia , Protocolos Clínicos , Anti-Inflamatórios não Esteroides/administração & dosagem , Expressão Gênica , Complicações Pós-Operatórias/prevenção & controleRESUMO
Las ránulas son seudoquistes resultantes de la extravasación salival de las glándulas sublinguales. Diversos tratamientos han sido empleados, no obstante, la marsupializaión se ha demostrado es el método más utilizado. La modificación de la técnica convencional, haciendo un taponamiento con gasas medicadas, presenta bajos índices de recurrencia, mientras su aplicación cuidadosa. El objetivo de este trabajo fue evaluar los resultados obtenidos por el empleo de la técnica de marsupialización modificada en los casos de ránulas intraorales diagnosticadas en el Servicio de Estomatología de la Facultad de Odontología de la Universidade Federal do Ceará, entre marzo de 1999 a diciembre de 2010, y comparar estos datos con estudios previamente reportados en la literatura. Los datos, tras su colecta, fueron tabulados y analizados estadísticamente (SPSS, versión 17.0). Del total de 2.103 biopsias, 17 (0.8%) correspondieron a ránulas intraorales, con edad comprendida entre 10 y 34 años de edad (media de 22,9 años), siendo 82,4 mujeres y 17,6 hombres. El tamaño de las lesiones varió entre 0,3 y 4 cm, con un promedio de aproximadamente 1,8 cm. La técnica de marsupialización modificada empleada en 13 pacientes, presentó un solo caso de recidiva. Otras dos recurrencias fueron observadas cuando se utilizó la técnica de la extirpación de la lesión, usada en cuatro casos. Nuestros resultados mostraron que la marsupialización, con cambio de la técnica convencional, es un método conservador eficaz, aunque no estadísticamente significativo (p>0,05), debiendo ser elegido como primera opción en el tratamiento de ránulas intraorales, con tasas reducidas de recurrencia.
Ranulas are pseudocysts as a result of salivary extravasation of the sublingual glands. Various treatments have been used, however, has been shown marsupialization the most used. The modification of the conventional technique, carefully filling of the lesion with gauze soaked in nitrofurazone (Furacin ®), have low rates of recurrence. The aim of this study was to evaluate the results obtained using the technique of marsupialization modified in the treatment of intraoral ranulas diagnosed in the Service of Stomatology, Faculty of Dentistry at the Universidade Federal do Ceará, from March 1999 to December 2010, and compare these data with previously reported studies in the literature. The data, after collection, were tabulated and statistically analyzed (SPSS, version 17.0). Of the total of 2,103 biopsies, 17 (0.8%) were intraoral ranulas, aged between 10 and 34 years of age (mean 22.9 years), with 82.4 men and 17.6 women. The lesion size ranged from 0.3 to 4 cm, with an average of about 1.8 cm. Modified marsupialization technique used in 13 patients, presented a single case of recurrence. Two other recurrences were observed when using the technique of surgical excision, used in four cases. Our results showed that marsupialization, with change of the conventional technique is an effective conservative approach, although not statistically significant (p> 0.05), must be chosen as first choice in the treatment of intraoral ranulas, with reduced rates of recurrence.
Assuntos
Humanos , Masculino , Adolescente , Adulto , Feminino , Criança , Adulto Jovem , Doenças Estomatognáticas/terapia , Rânula/terapia , Resultado do TratamentoRESUMO
Introdução: O Câncer Bucal representa atualmente um dosgraves problemas de saúde pública no Brasil. Conforme dados doInstituto Nacional do Câncer (INCA), para o ano de 2012, estimase14.170 novos casos. Objetivo: Avaliar o perfil epidemiológicode 23 pacientes portadores de neoplasias malignas atendidos emuma instituição odontológica de atenção secundária no períodoentre maio de 2007 e setembro de 2009. Método: Prontuáriosde 23 pacientes com resultado histopatológico de lesão malignada cavidade oral foral revisados. Gênero, idade, sítio anatômicoe associação com tabagismo e etilismo foram avaliados.Resultados: O carcinoma espinocelular foi o mais prevalente,correspondendo a 87% dos casos. Houve maior prevalência nogênero masculino (60,9%) e na faixa etária entre 50 e 60 anos.Os sítios anatômicos mais acometidos foram língua (34,8%) eassoalho bucal (21,7%). Verificou-se uma associação entre aocorrência das lesões malignas e o hábito de tabagismo umavez que, do total de pacientes acometidos, 47,8% eram fumantese 43,5% eram ex-fumantes. O perfil epidemiológico encontradocondiz com os achados de estudos anteriormente realizados.Conclusões: A caracterização dos casos de câncer bucalpermite definir o perfil epidemiológico dos pacientes acometidose possivelmente represente grande contribuição para oestabelecimento de políticas preventivas relacionadas à doença.
RESUMO
Adenoid cystic carcinoma is a common malignant neoplasm originated from salivary glands. The clinical and pathological findings typical of this tumor include slow growth, perineural invasion, and potential local recurrence. It accounts for nearly 2% to 4% of head and neck area tumors. In minor salivary glands it usually affects the palate. We described herein the case of a patient who presented a posterior tongue lesion, which was treated with surgery and radiotherapy as additional treatment. We also carried out a brief literature review on the subject