Detalhe da pesquisa
1.
HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis.
Mol Cell
; 78(6): 1237-1251.e7, 2020 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32442397
2.
Lead compound profiling for small molecule inhibitors of the REV1-CT/RIR Translesion synthesis Protein-Protein interaction.
Bioorg Med Chem
; 106: 117755, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38749343
3.
A platform utilizing Drosophila ovulation for nonhormonal contraceptive screening.
Proc Natl Acad Sci U S A
; 118(28)2021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260376
4.
DNA Sequence Specificity Reveals a Role of the HLTF HIRAN Domain in the Recognition of Trinucleotide Repeats.
Biochemistry
; 2022 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35608245
5.
Small molecules block the interaction between porcine reproductive and respiratory syndrome virus and CD163 receptor and the infection of pig cells.
Virol J
; 17(1): 116, 2020 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32727587
6.
Formulation and evaluation of itraconazole liposomes for Hedgehog pathway inhibition.
J Liposome Res
; 30(3): 305-311, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31576768
7.
Probing the Protein-Protein Interaction Between the ATRXADD Domain and the Histone H3 Tail.
Molecules
; 25(7)2020 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32218364
8.
Probing seco-steroid inhibition of the hedgehog signaling pathway.
Mol Cell Biochem
; 450(1-2): 75-85, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29876765
9.
Structural Approach To Identify a Lead Scaffold That Targets the Translesion Synthesis Polymerase Rev1.
J Chem Inf Model
; 58(11): 2266-2277, 2018 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30289707
10.
Small molecule scaffolds that disrupt the Rev1-CT/RIR protein-protein interaction.
Bioorg Med Chem
; 26(14): 4301-4309, 2018 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30037752
11.
A molecular dynamics approach to identify an oxysterol-based hedgehog pathway inhibitor.
Biochim Biophys Acta Gen Subj
; 1861(2): 168-177, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27825830
12.
Synthesis and evaluation of vitamin D3 analogues with C-11 modifications as inhibitors of Hedgehog signaling.
Bioorg Med Chem Lett
; 27(17): 4011-4014, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28780161
13.
Design, synthesis, and evaluation of hybrid vitamin D3 side chain analogues as hedgehog pathway inhibitors.
Bioorg Med Chem
; 23(3): 548-55, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25549899
14.
Small molecules that regulate the N6-methyladenosine RNA modification as potential anti-cancer agents.
Eur J Med Chem
; 274: 116526, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38805939
15.
Analogues of the Inhoffen-Lythgoe diol with anti-proliferative activity.
Bioorg Med Chem Lett
; 23(19): 5367-70, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23972439
16.
Development of Enterovirus Antiviral Agents That Target the Viral 2C Protein.
ChemMedChem
; 18(10): e202200541, 2023 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36792530
17.
Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathway.
Bioorg Med Chem Lett
; 22(14): 4859-63, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22687748
18.
The furan route to tropolones: probing the antiproliferative effects of ß-thujaplicin analogs.
Org Biomol Chem
; 10(43): 8597-604, 2012 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23032214
19.
Affinity-based protein profiling identifies vitamin D3 as a heat shock protein 70 antagonist that regulates hedgehog transduction in murine basal cell carcinoma.
Eur J Med Chem
; 228: 114005, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34844141
20.
Translesion DNA synthesis mediates acquired resistance to olaparib plus temozolomide in small cell lung cancer.
Sci Adv
; 8(19): eabn1229, 2022 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35559669