Detalhe da pesquisa
1.
Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes.
EMBO Rep
; 25(5): 2479-2510, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38684907
2.
Targeting TNFα produced by astrocytes expressing amyotrophic lateral sclerosis-linked mutant fused in sarcoma prevents neurodegeneration and motor dysfunction in mice.
Glia
; 70(7): 1426-1449, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35474517
3.
G-quadruplexes offer a conserved structural motif for NONO recruitment to NEAT1 architectural lncRNA.
Nucleic Acids Res
; 48(13): 7421-7438, 2020 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32496517
4.
The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease.
Nat Rev Neurosci
; 17(6): 383-95, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27150398
5.
The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.
Nature
; 525(7567): 56-61, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26308891
6.
C9orf72 nucleotide repeat structures initiate molecular cascades of disease.
Nature
; 507(7491): 195-200, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24598541
7.
FRET studies of a landscape of Lac repressor-mediated DNA loops.
Nucleic Acids Res
; 40(10): 4432-45, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22307389
8.
Differential response of C9orf72 transcripts following neuronal depolarization.
iScience
; 26(6): 106959, 2023 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37332610
9.
Breakdown of the central synapses in C9orf72-linked ALS/FTD.
Front Mol Neurosci
; 15: 1005112, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36187344
10.
A mouse model with widespread expression of the C9orf72-linked glycine-arginine dipeptide displays non-lethal ALS/FTD-like phenotypes.
Sci Rep
; 12(1): 5644, 2022 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35379876
11.
The effects of molecular crowding and CpG hypermethylation on DNA G-quadruplexes formed by the C9orf72 nucleotide repeat expansion.
Sci Rep
; 11(1): 23213, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34853325
12.
Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment.
EMBO Mol Med
; 12(5): e10722, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32347002
13.
Emerging role of RNAâ¢DNA hybrids in C9orf72-linked neurodegeneration.
Cell Cycle
; 14(4): 526-32, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25590632
14.
LacI-DNA-IPTG loops: equilibria among conformations by single-molecule FRET.
J Phys Chem B
; 117(16): 4713-22, 2013 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23406418
15.
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention.
Neuron
; 80(2): 415-28, 2013 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24139042