Detalhe da pesquisa
1.
ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids.
Cell
; 184(17): 4547-4563.e17, 2021 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34314701
2.
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
Cell
; 171(6): 1437-1452.e17, 2017 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29195078
3.
Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories.
Cell
; 156(1-2): 261-76, 2014 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24439381
4.
Dissecting OGT's TPR domain to identify determinants of cellular function.
Proc Natl Acad Sci U S A
; 121(22): e2401729121, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38768345
5.
A Cdk5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes.
Proc Natl Acad Sci U S A
; 120(16): e2217864120, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37043533
6.
Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca2+ entry and accelerated differentiation.
Mol Psychiatry
; 2023 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402854
7.
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling.
Cell
; 136(6): 1017-31, 2009 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19303846
8.
Chemically targeting the redox switch in AP1 transcription factor ΔFOSB.
Nucleic Acids Res
; 50(16): 9548-9567, 2022 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36039764
9.
Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility.
Mol Psychiatry
; 27(8): 3272-3285, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35505090
10.
Advances toward precision medicine for bipolar disorder: mechanisms & molecules.
Mol Psychiatry
; 26(1): 168-185, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32636474
11.
Phosphorylation-dependent control of Activity-regulated cytoskeleton-associated protein (Arc) protein by TNIK.
J Neurochem
; 158(5): 1058-1073, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34077555
12.
A psychiatric disease-related circular RNA controls synaptic gene expression and cognition.
Mol Psychiatry
; 25(11): 2712-2727, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31988434
13.
A microRNA cluster in the Fragile-X region expressed during spermatogenesis targets FMR1.
EMBO Rep
; 20(2)2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30573526
14.
A polygenic burden of rare disruptive mutations in schizophrenia.
Nature
; 506(7487): 185-90, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24463508
15.
Activation of WNT and CREB signaling pathways in human neuronal cells in response to the Omega-3 fatty acid docosahexaenoic acid (DHA).
Mol Cell Neurosci
; 99: 103386, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31202891
16.
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Proc Natl Acad Sci U S A
; 114(22): E4462-E4471, 2017 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28500272
17.
Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies.
Int J Mol Sci
; 21(23)2020 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33255694
18.
Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase.
Bioorg Med Chem Lett
; 29(15): 1962-1967, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31153805
19.
Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.
J Neurosci
; 37(41): 9917-9924, 2017 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28912154
20.
An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.
J Biol Chem
; 292(47): 19209-19225, 2017 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972160