Detalhe da pesquisa
1.
1,2,3-Triazole-totarol conjugates as potent PIP5K1α lipid kinase inhibitors.
Bioorg Med Chem
; 105: 117727, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38669736
2.
Natural Compounds Isolated from Stachybotrys chartarum Are Potent Inhibitors of Human Protein Kinase CK2.
Molecules
; 26(15)2021 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361605
3.
Design, synthesis and biological evaluation of new embelin derivatives as CK2 inhibitors.
Bioorg Chem
; 95: 103520, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31887475
4.
In Vitro and in Silico Evaluation of Bikaverin as a Potent Inhibitor of Human Protein Kinase CK2.
Molecules
; 24(7)2019 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30965682
5.
QSAR Model of Indeno[1,2-b]indole Derivatives and Identification of N-isopentyl-2-methyl-4,9-dioxo-4,9-Dihydronaphtho[2,3-b]furan-3-carboxamide as a Potent CK2 Inhibitor.
Molecules
; 25(1)2019 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31888043
6.
Impact of surgical complications on hospital costs and revenues: retrospective database study of Medicare claims.
J Comp Eff Res
; 12(7): e230080, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37350467
7.
In Silico and In Vitro Studies of Natural Compounds as Human CK2 Inhibitors.
Curr Comput Aided Drug Des
; 17(2): 323-331, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32160849
8.
Autodisplay of human PIP5K1α lipid kinase on Escherichia coli and inhibitor testing.
Enzyme Microb Technol
; 143: 109717, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375977
9.
Development of an in vitro screening assay for PIP5K1α lipid kinase and identification of potent inhibitors.
FEBS J
; 287(14): 3042-3064, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31876381
10.
Human αS1-casein induces IL-8 secretion by binding to the ecto-domain of the TLR4/MD2 receptor complex.
Biochim Biophys Acta Gen Subj
; 1863(3): 632-643, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30553868
11.
Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining.
Pharmaceuticals (Basel)
; 10(1)2017 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28075359
12.
Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas.
Clin Cancer Res
; 22(5): 1185-96, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26482041
13.
Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate.
Nat Biotechnol
; 34(11): 1161-1167, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27723727
14.
1st Joint European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC 2015).
Pharmaceuticals (Basel)
; 9(1)2015 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26712767
15.
Effects of novel 17alpha-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo.
J Steroid Biochem Mol Biol
; 84(5): 555-62, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12767280
16.
C16 and C17 substituted derivatives of pregnenolone and progesterone as inhibitors of 17alpha-hydroxylase-C17, 20-lyase: synthesis and biological evaluation.
Arch Pharm (Weinheim)
; 335(11-12): 526-34, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12596217
17.
Inhibition of CYP 17, a new strategy for the treatment of prostate cancer.
Arch Pharm (Weinheim)
; 335(4): 119-28, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12112031