RESUMO
We describe a patient who suffered from chronic progressive granulomatous lung disease. He had no clinical or microbiological evidence of infection. After failure of treatment with interferon-gamma and trimethoprim-sulfamethoxazole, he responded dramatically to corticosteroids.
Assuntos
Corticosteroides/uso terapêutico , Antivirais/farmacologia , Doença Granulomatosa Crônica/tratamento farmacológico , Interferon gama/farmacologia , Pneumopatias/congênito , Pneumopatias/tratamento farmacológico , Corticosteroides/farmacologia , Anti-Infecciosos/farmacologia , Criança , Progressão da Doença , Resistência a Medicamentos , Doença Granulomatosa Crônica/imunologia , Humanos , Pneumopatias/patologia , Masculino , Resultado do Tratamento , Combinação Trimetoprima e Sulfametoxazol/farmacologiaRESUMO
We report 13 patients with 16 episodes of acute lobar nephronia diagnosed in a prospective study that was conducted among 210 hospitalized children with urinary tract infection. In 30 episodes of urinary tract infection, a hypoechogenic or hyperechogenic lesion was found. Twenty patients underwent computed tomography, and in 16 of them acute lobar nephronia was diagnosed. Evolution to renal abscess occurred in 25%. Prolonged intravenous antibiotic treatment was sufficient in all cases.