Detalhe da pesquisa
1.
Tumor-induced stromal reprogramming drives lymph node transformation.
Nat Immunol
; 17(9): 1118-27, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27400148
2.
Interpreting the effect of mutations to protein binding sites from large-scale genomic screens.
Methods
; 222: 122-132, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38185227
3.
Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity.
Genes Dev
; 31(13): 1339-1353, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28790158
4.
Heterogeneity of the cancer cell line metabolic landscape.
Mol Syst Biol
; 18(11): e11006, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36321551
5.
Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance.
Nucleic Acids Res
; 49(10): 5588-5604, 2021 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33978741
6.
SARS-CoV-2 Variants Are Selecting for Spike Protein Mutations That Increase Protein Stability.
J Chem Inf Model
; 61(9): 4152-4155, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34472347
7.
Computational Saturation Screen Reveals the Landscape of Mutations in Human Fumarate Hydratase.
J Chem Inf Model
; 61(4): 1970-1980, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33848143
8.
Probing the Solution Structure of IκB Kinase (IKK) Subunit γ and Its Interaction with Kaposi Sarcoma-associated Herpes Virus Flice-interacting Protein and IKK Subunit ß by EPR Spectroscopy.
J Biol Chem
; 290(27): 16539-49, 2015 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25979343
9.
Emergent stem cell homeostasis in the C. elegans germline is revealed by hybrid modeling.
Biophys J
; 109(2): 428-38, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26200879
10.
Primary and secondary dimer interfaces of the fibroblast growth factor receptor 3 transmembrane domain: characterization via multiscale molecular dynamics simulations.
Biochemistry
; 53(2): 323-32, 2014 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24397339
11.
Large-scale computational modelling of the M1 and M2 synovial macrophages in rheumatoid arthritis.
NPJ Syst Biol Appl
; 10(1): 10, 2024 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38272919
12.
Understanding large scale sequencing datasets through changes to protein folding.
Brief Funct Genomics
; 2024 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38521964
13.
SMAD4 and KCNQ3 alterations are associated with lymph node metastases in oesophageal adenocarcinoma.
Biochim Biophys Acta Mol Basis Dis
; 1870(1): 166867, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37648039
14.
Mechanism of bacterial signal transduction revealed by molecular dynamics of Tsr dimers and trimers of dimers in lipid vesicles.
PLoS Comput Biol
; 8(9): e1002685, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23028283
15.
Mutations observed in somatic evolution reveal underlying gene mechanisms.
Commun Biol
; 6(1): 753, 2023 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37468606
16.
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.
Nat Genet
; 55(2): 232-245, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36658434
17.
Somatic mutations in facial skin from countries of contrasting skin cancer risk.
Nat Genet
; 55(9): 1440-1447, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37537257
18.
KCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas.
Life Sci Alliance
; 6(12)2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37748809
19.
How lipid headgroups sense the membrane environment: an application of ¹4N NMR.
Biophys J
; 103(6): 1245-53, 2012 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22995497
20.
Coarse-grain simulations reveal movement of the synaptobrevin C-terminus in response to piconewton forces.
Biophys J
; 103(5): 959-69, 2012 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23009845