Detalhe da pesquisa
1.
In vitro and in vivo induction of fetal hemoglobin with a reversible and selective DNMT1 inhibitor.
Haematologica
; 106(7): 1979-1987, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32586904
2.
Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes.
Haematologica
; 104(6): 1156-1167, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514804
3.
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).
Proc Natl Acad Sci U S A
; 109(8): 2989-94, 2012 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22323599
4.
Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine.
J Transl Med
; 9: 119, 2011 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21781349
5.
Potent inhibitors of HIV-1 integrase display a two-step, slow-binding inhibition mechanism which is absent in a drug-resistant T66I/M154I mutant.
Biochemistry
; 48(7): 1644-53, 2009 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19178153
6.
Complete DNA sequences of two oka strain varicella-zoster virus genomes.
J Virol
; 82(22): 11023-44, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18787000
7.
Temporal and spatial distribution of clonal complexes of Streptococcus pneumoniae isolates resistant to multiple classes of antibiotics in Belgium, 1997 to 2004.
Antimicrob Agents Chemother
; 52(9): 3216-20, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18573928
8.
Tumor-immune profiling of murine syngeneic tumor models as a framework to guide mechanistic studies and predict therapy response in distinct tumor microenvironments.
PLoS One
; 13(11): e0206223, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30388137
9.
BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer.
Cell Rep
; 22(3): 796-808, 2018 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29346775
10.
Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC).
Clin Cancer Res
; 24(13): 3149-3162, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29555663
11.
Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes.
JAMA Neurol
; 74(6): 677-685, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28437540
12.
Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress.
J Am Heart Assoc
; 6(5)2017 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28487390
13.
Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations.
BMC Infect Dis
; 2: 7, 2002 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12019036
14.
A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation.
Mol Cancer Ther
; 13(12): 3062-73, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25253781
15.
Sensitivity of cancer cells to Plk1 inhibitor GSK461364A is associated with loss of p53 function and chromosome instability.
Mol Cancer Ther
; 9(7): 2079-89, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20571075
16.
Molecular evolutionary analysis of cancer cell lines.
Mol Cancer Ther
; 9(2): 279-91, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20124449
17.
Comparative analysis of the complete nucleotide sequences of measles, mumps, and rubella strain genomes contained in Priorix-Tetra and ProQuad live attenuated combined vaccines.
Vaccine
; 27(16): 2265-73, 2009 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19428841
18.
Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL.
Cancer Res
; 69(17): 6871-8, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19671800