Detalhe da pesquisa
1.
An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns.
Genome Res
; 32(4): 778-790, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35210353
2.
A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry.
PLoS Genet
; 18(7): e1009977, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35788729
3.
Genetic architecture of RNA editing regulation in Alzheimer's disease across diverse ancestral populations.
Hum Mol Genet
; 31(17): 2876-2886, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35383839
4.
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.
Alzheimers Dement
; 19(6): 2538-2548, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36539198
5.
RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways.
Hum Mol Genet
; 28(18): 3053-3061, 2019 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31162550
6.
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
Mol Psychiatry
; 25(8): 1859-1875, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30108311
7.
Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
Mol Psychiatry
; 25(8): 1901-1903, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31636380
8.
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.
PLoS Genet
; 14(12): e1007791, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30517106
9.
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
Alzheimers Dement
; 17(7): 1179-1188, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33522086
10.
Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.
Genomics
; 111(4): 808-818, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29857119
11.
Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Alzheimers Dement
; 13(7): 727-738, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28183528
12.
Generalizability of Tau and Amyloid Plasma Biomarkers in Alzheimer's Disease Cohorts of Diverse Genetic Ancestries.
medRxiv
; 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38645114
13.
An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons.
Neurobiol Aging
; 131: 182-195, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37677864
14.
An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons.
bioRxiv
; 2023 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292815
15.
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.
medRxiv
; 2023 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37461624
16.
Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus.
Neurobiol Aging
; 104: 115.e1-115.e7, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33902942
17.
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
JAMA Neurol
; 78(1): 102-113, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33074286
18.
A modifier locus on chromosome 5 contributes to L1 cell adhesion molecule X-linked hydrocephalus in mice.
Neurogenetics
; 11(1): 53-71, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19565280
19.
Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease.
Nat Commun
; 11(1): 6114, 2020 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33257653
20.
Hadoop and PySpark for reproducibility and scalability of genomic sequencing studies.
Pac Symp Biocomput
; 25: 523-534, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31797624