Detalhe da pesquisa
1.
Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity.
Blood
; 115(17): 3520-30, 2010 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20197554
2.
INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology.
ACS Med Chem Lett
; 8(5): 486-491, 2017 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28523098
3.
dUTPase and uracil-DNA glycosylase are central modulators of antifolate toxicity in Saccharomyces cerevisiae.
Cancer Res
; 62(17): 4909-15, 2002 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12208740
4.
4-Aryl-1,2,3-triazole: a novel template for a reversible methionine aminopeptidase 2 inhibitor, optimized to inhibit angiogenesis in vivo.
J Med Chem
; 48(18): 5644-7, 2005 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16134930
5.
Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors.
Mol Cancer Ther
; 9(2): 489-98, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20124451
6.
Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model.
J Med Chem
; 52(23): 7364-7, 2009 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19507862
7.
Constitutive expression of angiopoietin-1 and -2 and modulation of their expression by inflammatory cytokines in rheumatoid arthritis synovial fibroblasts.
J Rheumatol
; 29(2): 230-9, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11838839