RESUMO
Chronic urticaria is the presence of wheals and/or angioedema, with daily or intermittent symptoms lasting more than 6 weeks. Although rarely life threatening, it can be a cause of significant embarrassment and misery. In most cases, no underlying factor is identified. It is therefore important to have a structured approach to the assessment in order to exclude important diagnoses, minimise costly screening tests and ensure a correct diagnosis is made. This article aims to highlight the importance of a focused history, provides a clear scheme for establishing a diagnosis and recommends when to perform appropriate investigations. A short discussion regarding treatment options and prognosis is also provided.
Assuntos
Anamnese , Urticária/diagnóstico , Urticária/etiologia , Criança , Doença Crônica , Diagnóstico Diferencial , Humanos , PrognósticoAssuntos
Corticosteroides/administração & dosagem , Corticosteroides/uso terapêutico , Infecções por Enterovirus/complicações , Infecções por Enterovirus/virologia , Enterovirus , Imunoglobulinas Intravenosas/administração & dosagem , Proteína Antagonista do Receptor de Interleucina 1/administração & dosagem , Linfo-Histiocitose Hemofagocítica/tratamento farmacológico , Linfo-Histiocitose Hemofagocítica/etiologia , Progressão da Doença , Quimioterapia Combinada , Enterovirus/fisiologia , Feminino , Humanos , Linfo-Histiocitose Hemofagocítica/diagnóstico , Masculino , Resultado do TratamentoRESUMO
BACKGROUND AND OBJECTIVES: Long-term prophylactic antibiotics are often used to prevent bacterial infections. However, supporting evidence for this is not always robust. Including parents in decisions relating to medication is key to medicines optimisation. Parental concern regarding medication is a major determinant of poor adherence. This study explores parental experiences of having a child prescribed prophylactic antibiotics and how that affects their antibiotic use behaviour. METHODS: We conducted a prospective, single-centre, exploratory, qualitative study at Sheffield Children's Hospital. Through 15 interviews, involving 18 participants, we explored parental 'lived experiences' and attitudes towards azithromycin prophylaxis prescribed for various respiratory conditions. Thematic analysis was conducted. RESULTS: The overriding factor influencing parental decisions about the uptake of antibiotic prophylaxis is wanting their child to be well now. The main concern voiced by parents is that of antibiotic resistance given their children are high users of antibiotics. This is however seen as a problem for the future, not the present. Preparing families adequately helps prevent practical difficulties relating to medication. Facilitating 'normalisation' of prophylaxis through daily routines and minimising disruption to the family environment may reduce parental anxiety, promote adherence and result in easing of potential restrictions to the child's daily activities. CONCLUSION: Grounded in our deeper understanding, we propose a behavioural model that describes phases parents go through while having a child on prophylactic antibiotics. Time invested in holistically addressing the parental experience and having an awareness of potential issues parents face, may facilitate medication adherence, reduce anxieties and improve doctor-parent relationships.