Pesquisa | Biblioteca Virtual em Saúde

1.

Fate mapping and scRNA sequencing reveal origin and diversity of lymph node stromal precursors.

Lenti, Elisa; Genovese, Luca; Bianchessi, Silvia; Maurizio, Aurora; Sain, Simona Baghai; di Lillo, Alessia; Mattavelli, Greta; Harel, Itamar; Bernassola, Francesca; Hehlgans, Thomas; Pfeffer, Klaus; Crosti, Mariacristina; Abrignani, Sergio; Evans, Sylvia M; Sitia, Giovanni; Guimarães-Camboa, Nuno; Russo, Vincenzo; van de Pavert, Serge A; Garcia-Manteiga, Jose Manuel; Brendolan, Andrea.

Immunity ; 55(4): 606-622.e6, 2022 04 12.

Artigo em Inglês | MEDLINE | ID: mdl-35358427

2.

A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate.

Harel, Itamar; Benayoun, Bérénice A; Machado, Ben; Singh, Param Priya; Hu, Chi-Kuo; Pech, Matthew F; Valenzano, Dario Riccardo; Zhang, Elisa; Sharp, Sabrina C; Artandi, Steven E; Brunet, Anne.

Cell ; 160(5): 1013-1026, 2015 Feb 26.

Artigo em Inglês | MEDLINE | ID: mdl-25684364

3.

The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan.

Valenzano, Dario Riccardo; Benayoun, Bérénice A; Singh, Param Priya; Zhang, Elisa; Etter, Paul D; Hu, Chi-Kuo; Clément-Ziza, Mathieu; Willemsen, David; Cui, Rongfeng; Harel, Itamar; Machado, Ben E; Yee, Muh-Ching; Sharp, Sabrina C; Bustamante, Carlos D; Beyer, Andreas; Johnson, Eric A; Brunet, Anne.

Cell ; 163(6): 1539-54, 2015 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-26638078

4.

Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responses.

Benayoun, Bérénice A; Pollina, Elizabeth A; Singh, Param Priya; Mahmoudi, Salah; Harel, Itamar; Casey, Kerriann M; Dulken, Ben W; Kundaje, Anshul; Brunet, Anne.

Genome Res ; 29(4): 697-709, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-30858345

5.

The turquoise killifish.

Harel, Itamar.

Nat Methods ; 19(10): 1150-1151, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36203025

6.

The actin regulator N-WASp is required for muscle-cell fusion in mice.

Gruenbaum-Cohen, Yael; Harel, Itamar; Umansky, Kfir-Baruch; Tzahor, Eldad; Snapper, Scott B; Shilo, Ben-Zion; Schejter, Eyal D.

Proc Natl Acad Sci U S A ; 109(28): 11211-6, 2012 Jul 10.

Artigo em Inglês | MEDLINE | ID: mdl-22736793

7.

Pharyngeal mesoderm regulatory network controls cardiac and head muscle morphogenesis.

Harel, Itamar; Maezawa, Yoshiro; Avraham, Roi; Rinon, Ariel; Ma, Hsiao-Yen; Cross, Joe W; Leviatan, Noam; Hegesh, Julius; Roy, Achira; Jacob-Hirsch, Jasmine; Rechavi, Gideon; Carvajal, Jaime; Tole, Shubha; Kioussi, Chrissa; Quaggin, Susan; Tzahor, Eldad.

Proc Natl Acad Sci U S A ; 109(46): 18839-44, 2012 Nov 13.

Artigo em Inglês | MEDLINE | ID: mdl-23112163

8.

Tissue-specific landscape of protein aggregation and quality control in an aging vertebrate.

Chen, Yiwen R; Harel, Itamar; Singh, Param Priya; Ziv, Inbal; Moses, Eitan; Goshtchevsky, Uri; Machado, Ben E; Brunet, Anne; Jarosz, Daniel F.

Dev Cell ; 2024 May 24.

Artigo em Inglês | MEDLINE | ID: mdl-38810654

9.

The killifish germline regulates longevity and somatic repair in a sex-specific manner.

Moses, Eitan; Atlan, Tehila; Sun, Xue; Franek, Roman; Siddiqui, Atif; Marinov, Georgi K; Shifman, Sagiv; Zucker, David M; Oron-Gottesman, Adi; Greenleaf, William J; Cohen, Ehud; Ram, Oren; Harel, Itamar.

bioRxiv ; 2024 May 12.

Artigo em Inglês | MEDLINE | ID: mdl-38187630

10.

The killifish germline regulates longevity and somatic repair in a sex-specific manner.

Moses, Eitan; Atlan, Tehila; Sun, Xue; Franek, Roman; Siddiqui, Atif; Marinov, Georgi K; Shifman, Sagiv; Zucker, David M; Oron-Gottesman, Adi; Greenleaf, William J; Cohen, Ehud; Ram, Oren; Harel, Itamar.

Nat Aging ; 2024 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-38750187

11.

Identification of protein aggregates in the aging vertebrate brain with prion-like and phase-separation properties.

Harel, Itamar; Chen, Yiwen R; Ziv, Inbal; Singh, Param Priya; Heinzer, Daniel; Navarro Negredo, Paloma; Goshtchevsky, Uri; Wang, Wei; Astre, Gwendoline; Moses, Eitan; McKay, Andrew; Machado, Ben E; Hebestreit, Katja; Yin, Sifei; Sánchez Alvarado, Alejandro; Jarosz, Daniel F; Brunet, Anne.

Cell Rep ; : 112787, 2024 May 24.

Artigo em Inglês | MEDLINE | ID: mdl-38810650

12.

The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature.

Theis, Susanne; Patel, Ketan; Valasek, Petr; Otto, Anthony; Pu, Qin; Harel, Itamar; Tzahor, Eldad; Tajbakhsh, Shahragim; Christ, Bodo; Huang, Ruijin.

Development ; 137(17): 2961-71, 2010 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-20699298

13.

CRISPR-Cas9 Genome Editing in Nothobranchius furzeri for Gene Knockout and Knock-In.

Rozenberg, Itai; Moses, Eitan; Harel, Itamar.

Cold Spring Harb Protoc ; 2023(2): 90-99, 2023 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-36223984

14.

A scalable and tunable platform for functional interrogation of peptide hormones in fish.

Moses, Eitan; Franek, Roman; Harel, Itamar.

Elife ; 122023 10 24.

Artigo em Inglês | MEDLINE | ID: mdl-37872843

15.

Genetic perturbation of AMP biosynthesis extends lifespan and restores metabolic health in a naturally short-lived vertebrate.

Astre, Gwendoline; Atlan, Tehila; Goshtchevsky, Uri; Oron-Gottesman, Adi; Smirnov, Margarita; Shapira, Kobi; Velan, Ariel; Deelen, Joris; Levy, Tomer; Levanon, Erez Y; Harel, Itamar.

Dev Cell ; 58(15): 1350-1364.e10, 2023 08 07.

Artigo em Inglês | MEDLINE | ID: mdl-37321215

16.

Efficient genome engineering approaches for the short-lived African turquoise killifish.

Harel, Itamar; Valenzano, Dario Riccardo; Brunet, Anne.

Nat Protoc ; 11(10): 2010-2028, 2016 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-27658015

17.

The African Turquoise Killifish: A Model for Exploring Vertebrate Aging and Diseases in the Fast Lane.

Harel, Itamar; Brunet, Anne.

Cold Spring Harb Symp Quant Biol ; 80: 275-9, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26642856

18.

Comprehensive transcriptome analysis using synthetic long-read sequencing reveals molecular co-association of distant splicing events.

Tilgner, Hagen; Jahanbani, Fereshteh; Blauwkamp, Tim; Moshrefi, Ali; Jaeger, Erich; Chen, Feng; Harel, Itamar; Bustamante, Carlos D; Rasmussen, Morten; Snyder, Michael P.

Nat Biotechnol ; 33(7): 736-42, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25985263

19.

Distinct origins and genetic programs of head muscle satellite cells.

Harel, Itamar; Nathan, Elisha; Tirosh-Finkel, Libbat; Zigdon, Hila; Guimarães-Camboa, Nuno; Evans, Sylvia M; Tzahor, Eldad.

Dev Cell ; 16(6): 822-32, 2009 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-19531353

20.

Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis.

Van Keymeulen, Alexandra; Mascre, Guilhem; Youseff, Khalil Kass; Harel, Itamar; Michaux, Cindy; De Geest, Natalie; Szpalski, Caroline; Achouri, Younes; Bloch, Wilhelm; Hassan, Bassem A; Blanpain, Cédric.

J Cell Biol ; 187(1): 91-100, 2009 Oct 05.

Artigo em Inglês | MEDLINE | ID: mdl-19786578

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Fate mapping and scRNA sequencing reveal origin and diversity of lymph node stromal precursors.

A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate.

The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan.

Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responses.

The turquoise killifish.

The actin regulator N-WASp is required for muscle-cell fusion in mice.

Pharyngeal mesoderm regulatory network controls cardiac and head muscle morphogenesis.

Tissue-specific landscape of protein aggregation and quality control in an aging vertebrate.

The killifish germline regulates longevity and somatic repair in a sex-specific manner.

The killifish germline regulates longevity and somatic repair in a sex-specific manner.

Identification of protein aggregates in the aging vertebrate brain with prion-like and phase-separation properties.

The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature.

CRISPR-Cas9 Genome Editing in Nothobranchius furzeri for Gene Knockout and Knock-In.

A scalable and tunable platform for functional interrogation of peptide hormones in fish.

Genetic perturbation of AMP biosynthesis extends lifespan and restores metabolic health in a naturally short-lived vertebrate.

Efficient genome engineering approaches for the short-lived African turquoise killifish.

The African Turquoise Killifish: A Model for Exploring Vertebrate Aging and Diseases in the Fast Lane.

Comprehensive transcriptome analysis using synthetic long-read sequencing reveals molecular co-association of distant splicing events.

Distinct origins and genetic programs of head muscle satellite cells.

Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis.