Detalhe da pesquisa
1.
Alternate aerosol and systemic immunisation with a recombinant viral vector for tuberculosis, MVA85A: A phase I randomised controlled trial.
PLoS Med
; 16(4): e1002790, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31039172
2.
Gene expression and cytokine profile correlate with mycobacterial growth in a human BCG challenge model.
J Infect Dis
; 211(9): 1499-509, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25381367
3.
Evaluation of a human BCG challenge model to assess antimycobacterial immunity induced by BCG and a candidate tuberculosis vaccine, MVA85A, alone and in combination.
J Infect Dis
; 209(8): 1259-68, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24273174
4.
Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.
BMC Infect Dis
; 14: 314, 2014 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24912498
5.
Evaluation of immune profiles associated with control of mycobacterial growth in systemic lupus erythematosus (SLE) patients.
Tuberculosis (Edinb)
; 148: 102533, 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38878478
6.
Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial.
Lancet Infect Dis
; 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38621405
7.
Safety, tolerability, viral kinetics, and immune correlates of protection in healthy, seropositive UK adults inoculated with SARS-CoV-2: a single-centre, open-label, phase 1 controlled human infection study.
Lancet Microbe
; 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38703782
8.
Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants.
Nat Commun
; 13(1): 6594, 2022 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36329009
9.
Functional in-vitro evaluation of the non-specific effects of BCG vaccination in a randomised controlled clinical study.
Sci Rep
; 12(1): 7808, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35552463
10.
A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates.
NPJ Vaccines
; 6(1): 3, 2021 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33397986
11.
The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells.
F1000Res
; 10: 257, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33976866
12.
Induction of Functional Specific Antibodies, IgG-Secreting Plasmablasts and Memory B Cells Following BCG Vaccination.
Front Immunol
; 12: 798207, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35069580
13.
Phase I Trial Evaluating the Safety and Immunogenicity of Candidate TB Vaccine MVA85A, Delivered by Aerosol to Healthy M.tb-Infected Adults.
Vaccines (Basel)
; 9(4)2021 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33923628
14.
Tools for Assessing the Protective Efficacy of TB Vaccines in Humans: in vitro Mycobacterial Growth Inhibition Predicts Outcome of in vivo Mycobacterial Infection.
Front Immunol
; 10: 2983, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31998295
15.
Cytomegalovirus infection is a risk factor for tuberculosis disease in infants.
JCI Insight
; 4(23)2019 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697647
16.
Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection.
Sci Rep
; 8(1): 14480, 2018 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30262883
17.
Development of a non-human primate BCG infection model for the evaluation of candidate tuberculosis vaccines.
Tuberculosis (Edinb)
; 108: 99-105, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29523335
18.
Assay optimisation and technology transfer for multi-site immuno-monitoring in vaccine trials.
PLoS One
; 12(10): e0184391, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29020010
19.
T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Nat Commun
; 7: 11290, 2016 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27068708
20.
A Phase I, Open-Label Trial, Evaluating the Safety and Immunogenicity of Candidate Tuberculosis Vaccines AERAS-402 and MVA85A, Administered by Prime-Boost Regime in BCG-Vaccinated Healthy Adults.
PLoS One
; 10(11): e0141687, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26529238