Detalhe da pesquisa
1.
A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies.
Acta Neuropathol
; 142(3): 399-421, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34309760
2.
Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro.
Molecules
; 25(3)2020 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32013170
3.
Defined astrocytic expression of human amyloid precursor protein in Tg2576 mouse brain.
Glia
; 67(2): 393-403, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30485540
4.
Immunohistochemical Evidence from APP-Transgenic Mice for Glutaminyl Cyclase as Drug Target to Diminish pE-Abeta Formation.
Molecules
; 23(4)2018 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29673150
5.
Identification of thyrotropin-releasing hormone as hippocampal glutaminyl cyclase substrate in neurons and reactive astrocytes.
Biochim Biophys Acta
; 1852(1): 146-55, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25446989
6.
Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer's disease.
Acta Neuropathol
; 129(4): 565-83, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25666182
7.
Young human alpha synuclein transgenic (BAC-SNCA) mice display sex- and gene-dose-dependent phenotypic disturbances.
Behav Brain Res
; 460: 114781, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38043677
8.
Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aß is induced by pyroglutamate-Aß formation.
J Neurosci
; 31(36): 12790-801, 2011 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21900558
9.
Immunohistochemical Demonstration of the pGlu79 α-Synuclein Fragment in Alzheimer's Disease and Its Tg2576 Mouse Model.
Biomolecules
; 12(7)2022 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35883562
10.
Alpha synuclein processing by MMP-3 - implications for synucleinopathies.
Behav Brain Res
; 434: 114020, 2022 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35870616
11.
Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aß deposits in hippocampus via distinct cellular mechanisms.
Acta Neuropathol
; 121(6): 705-19, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21301857
12.
Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease.
Acta Neuropathol
; 120(2): 195-207, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20383514
13.
Targeting isoaspartate-modified Aß rescues behavioral deficits in transgenic mice with Alzheimer's disease-like pathology.
Alzheimers Res Ther
; 12(1): 149, 2020 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33189132
14.
Cell Type-Specific Human APP Transgene Expression by Hippocampal Interneurons in the Tg2576 Mouse Model of Alzheimer's Disease.
Front Neurosci
; 13: 137, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30853883
15.
Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, co-aggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheimer's disease.
Acta Neuropathol Commun
; 7(1): 79, 2019 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31109380
16.
QUINT: Workflow for Quantification and Spatial Analysis of Features in Histological Images From Rodent Brain.
Front Neuroinform
; 13: 75, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31849633
17.
Sex- and age-specific modulation of brain GABA levels in a mouse model of Alzheimer's disease.
Neurobiol Aging
; 62: 168-179, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29154037
18.
Dipeptidyl-Peptidase Activity of Meprin ß Links N-truncation of Aß with Glutaminyl Cyclase-Catalyzed pGlu-Aß Formation.
J Alzheimers Dis
; 66(1): 359-375, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30320570
19.
Region and lamina-specific distribution of extracellular matrix proteoglycans, hyaluronan and tenascin-R in the mouse hippocampal formation.
J Chem Neuroanat
; 26(1): 37-50, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12954529
20.
Tenascin-R promotes assembly of the extracellular matrix of perineuronal nets via clustering of aggrecan.
Philos Trans R Soc Lond B Biol Sci
; 369(1654): 20140046, 2014 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25225104