Detalhe da pesquisa
1.
Benzo(a)pyrene-7,8-dihydrodiol 9,10-oxide adenosine and deoxyadenosine adducts: structure and stereochemistry.
Science
; 206(4424): 1309-11, 1979 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-316186
2.
Benzo(a)pyrene diol epoxides as intermediates in nucleic acid binding in vitro and in vivo.
Science
; 193(4253): 592-5, 1976 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-959820
3.
Comparison of the cellular DNA-bound products of benzo(alpha)pyrene with the products formed by the reaction of benzo(alpha)pyrene-4,5-oxide with DNA.
Cancer Res
; 35(1): 54-7, 1975 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-1167347
4.
Oxidation of the trans-3,4-dihydrodiol metabolites of the potent carcinogen 7,12-dimethylbenz(a)anthracene and other benz(a)anthracene derivatives by 3 alpha-hydroxysteroid-dihydrodiol dehydrogenase: effects of methyl substitution on velocity and stereochemical course of trans-dihydrodiol oxidation.
Cancer Res
; 48(5): 1227-32, 1988 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-3124956
5.
Molecular structure of the K-region cis-dihydrodiol of 7,12-dimethylbenz[a]anthracene.
Cancer Res
; 37(3): 775-82, 1977 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-402208
6.
Molecular structure of benzo(a)pyrene 4,5-oxide.
Cancer Res
; 36(11 Pt 1): 3951-7, 1976 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-975043
7.
Identification of the major adducts formed by reaction of 5-methylchrysene anti-dihydrodiol-epoxides with DNA in vitro.
Cancer Res
; 44(6): 2524-9, 1984 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-6547075
8.
Influence of the alkyl substituent on mutagenicity and covalent DNA binding of bay region diol-epoxides of 7-methyl- and 7-ethylbenz(a)anthracene in Salmonella and V79 Chinese hamster cells.
Cancer Res
; 49(7): 1778-82, 1989 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-2647293
9.
Potent tumor-initiating activity of the 3,4-dihydrodiol of 7,12-dimethylbenz(a)anthracene in mouse skin.
Cancer Res
; 39(6 Pt 1): 1934-6, 1979 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-109189
10.
Carcinogenicity and mutagenicity of benz(a)anthracene diols and diol-epoxides.
Cancer Res
; 38(6): 1699-704, 1978 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-647680
11.
Reactivity with DNA bases and mutagenicity toward Salmonella typhimurium of methylchrysene diol epoxide enantiomers.
Cancer Res
; 48(7): 1781-7, 1988 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-3258179
12.
Metabolic activation of benzo[g]chrysene in the human mammary carcinoma cell line MCF-7.
Cancer Res
; 57(3): 415-9, 1997 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-9012467
13.
Enhancing effect of a bay region methyl group on tumorigenicity in newborn mice and mouse skin of enantiomeric bay region diol epoxides formed stereoselectively from methylchrysenes in mouse epidermis.
Cancer Res
; 47(20): 5310-5, 1987 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-3652037
14.
Age-, tissue-, and Ah genotype-dependent differences in the binding of 3-methylcholanthrene and its metabolite(s) to mouse DNA.
Cancer Res
; 50(14): 4239-47, 1990 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-2364382
15.
High stereoselectivity in mouse skin metabolic activation of methylchrysenes to tumorigenic dihydrodiols.
Cancer Res
; 47(14): 3613-7, 1987 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-3594428
16.
Rates of hydrolysis and extents of DNA binding of 5-methylchrysene dihydrodiol epoxides.
Cancer Res
; 45(5): 1990-6, 1985 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-3986755
17.
Tumorigenicity of 5-methylchrysene dihydrodiols and dihydrodiol epoxides in newborn mice and on mouse skin.
Cancer Res
; 45(4): 1449-52, 1985 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-3838497
18.
Both (+/-)syn- and (+/-)anti-7,12-dimethylbenz[a]anthracene-3,4-diol-1,2-epoxides initiate tumors in mouse skin that possess -CAA- to -CTA- mutations at Codon 61 of c-H-ras.
Cancer Res
; 60(20): 5688-95, 2000 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11059761
19.
Synthesis of the tumorigenic 3,4-dihydrodiol metabolites of dibenz[a,j]anthracene and 7,14-dimethyldibenz[a,j]anthracene.
J Med Chem
; 31(7): 1308-12, 1988 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-3385726
20.
Biologically active dihydrodiol metabolites of polycyclic aromatic hydrocarbons structurally related to the potent carcinogenic hydrocarbon 7,12-dimethylbenz[a]anthracene.
J Med Chem
; 31(1): 154-9, 1988 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-3121856