RESUMO
Langerhans cell histiocytosis (LCH) is a relatively rare disease affecting the reticuloendothelial system in the pediatric age group. It can affect bones, lung, liver, spleen, lymph nodes and skin. MR imaging is particularly informative in diagnosis and management of bone LCH. In this report, we present the initial and 23 months post-treatment MR images of a femoral LCH lesion in a 12-year-old child to describe the role of MRI in bone LCH.
Assuntos
Doenças Ósseas/diagnóstico por imagem , Fêmur/diagnóstico por imagem , Histiocitose de Células de Langerhans/diagnóstico por imagem , Doenças Ósseas/tratamento farmacológico , Criança , Feminino , Fêmur/patologia , Histiocitose de Células de Langerhans/tratamento farmacológico , Humanos , Imageamento por Ressonância Magnética , Radiografia , Resultado do TratamentoRESUMO
A 3-year-old boy receiving valproate for 1.5 months presented with sudden-onset unprovoked seizures and unconsciousness. Hypoketotic hypoglycemia, hyperammonemia, and deranged liver function were detected. Elevated medium-chain urinary acylglycines and plasma acylcarnitine were detected. His serum valproate level was elevated. Valproate toxicity had been precipitated in presence of medium-chain acyl-CoA dehydrogenase deficiency. Cranial magnetic resonance imaging brain indicated unilateral basal ganglia ischemia instead of the bilateral changes expected in metabolic disease.
Assuntos
Erros Inatos do Metabolismo Lipídico/patologia , Acil-CoA Desidrogenase/deficiência , Anticonvulsivantes/efeitos adversos , Anticonvulsivantes/farmacocinética , Anticonvulsivantes/uso terapêutico , Gânglios da Base/patologia , Encéfalo/patologia , Isquemia Encefálica/patologia , Carnitina/análogos & derivados , Carnitina/sangue , Infarto Cerebral/patologia , Pré-Escolar , Escala de Coma de Glasgow , Humanos , Testes de Função Hepática , Imageamento por Ressonância Magnética , Masculino , Respiração Artificial , Convulsões/tratamento farmacológico , Convulsões/etiologia , Ácido Valproico/efeitos adversos , Ácido Valproico/farmacocinética , Ácido Valproico/uso terapêuticoRESUMO
Trigeminal neuralgia is a painful condition affecting face. Its commonest cause is the tortuous vessels in prepontine cistern. There are other causes also, like brainstem lesions and mass lesions, as well as inflammatory causes. We present a case of an HIV patient with marked involvement of trigeminal nerves, which is a unique finding in immunocompromised patients.
RESUMO
A 17-year-old girl presented with features of biliary obstruction. Magnetic resonance cholangi-pancreatography revealed typical linear signals in common bile duct, which appears like Ascaris lumbricoides. The diagnosis was confirmed by endoscopic removal of the worm.