Detalhe da pesquisa
1.
Dapagliflozin dampens liver fibrosis induced by common bile duct ligation in rats associated with the augmentation of the hepatic Sirt1/AMPK/PGC1α/FoxO1 axis.
Toxicol Appl Pharmacol
; 489: 116991, 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38871090
2.
New 2-oxoindole derivatives as multiple PDGFRα/ß and VEGFR-2 tyrosine kinase inhibitors.
Bioorg Chem
; 145: 107234, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38412650
3.
Metabolomics approach of Symphyotrichum squamatum ethanol extract and its nano-Ag formulation protective effect on gastric ulcer via bio-chemical and pathological analyses.
Biomarkers
; 28(2): 190-205, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36484430
4.
New antiproliferative 3-substituted oxindoles inhibiting EGFR/VEGFR-2 and tubulin polymerization.
Mol Divers
; 2023 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36790582
5.
Development and Assessment of 1,5-Diarylpyrazole/Oxime Hybrids Targeting EGFR and JNK-2 as Antiproliferative Agents: A Comprehensive Study through Synthesis, Molecular Docking, and Evaluation.
Molecules
; 28(18)2023 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37764297
6.
Gastro-protective effect of Artemisia Sieberi essential oil against ethanol-induced ulcer in rats as revealed via biochemical, histopathological and metabolomics analysis.
Biomarkers
; 27(3): 247-257, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-34978233
7.
Design, synthesis, in vitro antiproliferative evaluation and in silico studies of new VEGFR-2 inhibitors based on 4-piperazinylquinolin-2(1H)-one scaffold.
Bioorg Chem
; 120: 105631, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35091289
8.
Novel 4-(piperazin-1-yl)quinolin-2(1H)-one bearing thiazoles with antiproliferative activity through VEGFR-2-TK inhibition.
Bioorg Med Chem
; 40: 116168, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33962153
9.
Design and synthesis of novel quinoline/chalcone/1,2,4-triazole hybrids as potent antiproliferative agent targeting EGFR and BRAFV600E kinases.
Bioorg Chem
; 106: 104510, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33279248
10.
Topical Wound Healing Activity of Myricetin Isolated from Tecomaria capensis v. aurea.
Molecules
; 25(21)2020 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33105570
11.
New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity.
Bioorg Chem
; 82: 360-377, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30428415
12.
Topical Eugenol Successfully Treats Experimental Candida albicans-Induced Keratitis.
Ophthalmic Res
; 60(2): 69-79, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29969774
13.
Recent updates of fluoroquinolones as antibacterial agents.
Arch Pharm (Weinheim)
; 351(9): e1800141, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30048015
14.
Biochemical Analysis of Four Missense Mutations in the HSD17B3 Gene Associated With 46,XY Disorders of Sex Development in Egyptian Patients.
J Sex Med
; 14(9): 1165-1174, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28859874
15.
Novel quinoline incorporating 1,2,4-triazole/oxime hybrids: Synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations.
Bioorg Chem
; 75: 242-259, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29032325
16.
Design, synthesis, molecular docking, anti-Proteus mirabilis and urease inhibition of new fluoroquinolone carboxylic acid derivatives.
Bioorg Chem
; 70: 1-11, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27908539
17.
Telmisartan and candesartan promote browning of white adipose tissue and reverse fatty liver changes in high fat diet fed male albino rats.
Naunyn Schmiedebergs Arch Pharmacol
; 397(4): 2359-2378, 2024 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37831115
18.
Ameliorative effects of androstenediol against acetic acid-induced colitis in male wistar rats via inhibiting TLR4-mediated PI3K/Akt and NF-κB pathways through estrogen receptor ß activation.
Int Immunopharmacol
; 127: 111414, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38141404
19.
Correction: Ammar et al. Protective Effects of Naringenin from Citrus sinensis (var. Valencia) Peels against CCl4-Induced Hepatic and Renal Injuries in Rats Assessed by Metabolomics, Histological and Biochemical Analyses. Nutrients 2022, 14, 841.
Nutrients
; 16(3)2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38337749
20.
Indole-based FLT3 inhibitors and related scaffolds as potential therapeutic agents for acute myeloid leukemia.
BMC Chem
; 17(1): 73, 2023 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37438819