Detalhe da pesquisa
1.
Apolipoprotein E/Amyloid-ß Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4.
Am J Pathol
; 189(8): 1621-1636, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31108099
2.
Familial Alzheimer's Disease Mutations within the Amyloid Precursor Protein Alter the Aggregation and Conformation of the Amyloid-ß Peptide.
J Biol Chem
; 292(8): 3172-3185, 2017 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049728
3.
Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-ß.
Nature
; 485(7400): 651-5, 2012 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22660329
4.
Monoclonal antibodies against Aß42 fibrils distinguish multiple aggregation state polymorphisms in vitro and in Alzheimer disease brain.
J Biol Chem
; 289(46): 32131-32143, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25281743
5.
Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques.
Neurobiol Dis
; 71: 53-61, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092575
6.
Distinct Patterns of Gene Expression Changes in the Colon and Striatum of Young Mice Overexpressing Alpha-Synuclein Support Parkinson's Disease as a Multi-System Process.
J Parkinsons Dis
; 13(7): 1127-1147, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37638450
7.
Behavioral Deficits and Brain α-Synuclein and Phosphorylated Serine-129 α-Synuclein in Male and Female Mice Overexpressing Human α-Synuclein.
J Alzheimers Dis
; 79(2): 875-893, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33361597
8.
Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.
Mol Brain
; 14(1): 70, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33875010
9.
Trapping and Characterization of Nontoxic Aß42 Aggregation Intermediates.
ACS Chem Neurosci
; 10(8): 3880-3887, 2019 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31319029
10.
Deuterium-reinforced linoleic acid lowers lipid peroxidation and mitigates cognitive impairment in the Q140 knock in mouse model of Huntington's disease.
FEBS J
; 285(16): 3002-3012, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29933522
11.
A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.
Sci Rep
; 8(1): 17574, 2018 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514854
12.
Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice.
Stem Cell Reports
; 10(1): 58-72, 2018 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29233555
13.
The Anti-Amyloid-ß Monoclonal Antibody 4G8 Recognizes a Generic Sequence-Independent Epitope Associated with α-Synuclein and Islet Amyloid Polypeptide Amyloid Fibrils.
J Alzheimers Dis
; 50(2): 517-25, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26682688
14.
Correction to: Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.
Mol Brain
; 14(1): 108, 2021 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34238327
15.
Effective anti-Alzheimer Aß therapy involves depletion of specific Aß oligomer subtypes.
Neurol Neuroimmunol Neuroinflamm
; 3(3): e237, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27218118
16.
Transgenic rodent models to study alpha-synuclein pathogenesis, with a focus on cognitive deficits.
Curr Top Behav Neurosci
; 22: 303-30, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25218491