Detalhe da pesquisa
1.
Dissection of MKK6 and p38 Signaling Using Light-Activated Protein Kinases.
Chembiochem
; 25(1): e202300551, 2024 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37856284
2.
G-actin diffusion is insufficient to achieve F-actin assembly in fast-treadmilling protrusions.
Biophys J
; 122(18): 3816-3829, 2023 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37644720
3.
A kinetic model of phospholipase C-γ1 linking structure-based insights to dynamics of enzyme autoinhibition and activation.
J Biol Chem
; 298(5): 101886, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35367415
4.
Semi-autonomous wound invasion via matrix-deposited, haptotactic cues.
J Theor Biol
; 568: 111506, 2023 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37094713
5.
Modeling cell protrusion predicts how myosin II and actin turnover affect adhesion-based signaling.
Biophys J
; 121(1): 102-118, 2022 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34861242
6.
Optical control of MAP kinase kinase 6 (MKK6) reveals that it has divergent roles in pro-apoptotic and anti-proliferative signaling.
J Biol Chem
; 295(25): 8494-8504, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32371393
7.
Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing.
PLoS Comput Biol
; 16(4): e1007708, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32255775
8.
Kinetic Modeling and Analysis of the Akt/Mechanistic Target of Rapamycin Complex 1 (mTORC1) Signaling Axis Reveals Cooperative, Feedforward Regulation.
J Biol Chem
; 292(7): 2866-2872, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28069808
9.
Lamellipodia are crucial for haptotactic sensing and response.
J Cell Sci
; 129(12): 2329-42, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27173494
10.
A Reaction-Diffusion Model Explains Amplification of the PLC/PKC Pathway in Fibroblast Chemotaxis.
Biophys J
; 113(1): 185-194, 2017 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28700916
11.
Are Filopodia Privileged Signaling Structures in Migrating Cells?
Biophys J
; 111(9): 1827-1830, 2016 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27712827
12.
Data-driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states.
Mol Syst Biol
; 10: 718, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24489118
13.
Deactivation of a negative regulator: a distinct signal transduction mechanism, pronounced in Akt signaling.
Biophys J
; 107(10): L29-32, 2014 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25418317
14.
Quantifying collective motion patterns in mesenchymal cell populations using topological data analysis and agent-based modeling.
Math Biosci
; 370: 109158, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38373479
15.
Data-driven modelling of receptor tyrosine kinase signalling networks quantifies receptor-specific potencies of PI3K- and Ras-dependent ERK activation.
Biochem J
; 441(1): 77-85, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21943356
16.
On the inference of ERK signaling dynamics from protein biosensor measurements.
Mol Biol Cell
; 34(6): ar60, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36884295
17.
Isoform-specific optical activation of kinase function reveals p38-ERK signaling crosstalk.
RSC Chem Biol
; 4(10): 765-773, 2023 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37799579
18.
Live-cell fluorescence microscopy with molecular biosensors: what are we really measuring?
Biophys J
; 102(9): 2003-11, 2012 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22824263
19.
Allosteric modulation of Ras-GTP is linked to signal transduction through RAF kinase.
J Biol Chem
; 286(5): 3323-31, 2011 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21098031
20.
In chemotaxing fibroblasts, both high-fidelity and weakly biased cell movements track the localization of PI3K signaling.
Biophys J
; 100(8): 1893-901, 2011 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21504725