Detalhe da pesquisa
1.
Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss.
Am J Hum Genet
; 109(6): 1077-1091, 2022 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35580588
2.
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
Nature
; 570(7759): 71-76, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31118516
3.
Key variants via the Alzheimer's Disease Sequencing Project whole genome sequence data.
Alzheimers Dement
; 20(5): 3290-3304, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38511601
4.
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Proc Natl Acad Sci U S A
; 117(5): 2560-2569, 2020 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31964835
5.
Whole-Genome Sequencing Association Analyses of Stroke and Its Subtypes in Ancestrally Diverse Populations From Trans-Omics for Precision Medicine Project.
Stroke
; 53(3): 875-885, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34727735
6.
A System for Phenotype Harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Program.
Am J Epidemiol
; 190(10): 1977-1992, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33861317
7.
New genetic loci link adipose and insulin biology to body fat distribution.
Nature
; 518(7538): 187-196, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25673412
8.
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
PLoS Genet
; 13(4): e1006528, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28448500
9.
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
PLoS Genet
; 13(8): e1006972, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28832619
10.
Association of Severe Hypercholesterolemia and Familial Hypercholesterolemia Genotype With Risk of Coronary Heart Disease.
Circulation
; 147(20): 1556-1559, 2023 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37186683
11.
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
PLoS Genet
; 12(6): e1006166, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27355579
12.
FTO genotype is associated with phenotypic variability of body mass index.
Nature
; 490(7419): 267-72, 2012 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22982992
13.
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
PLoS Genet
; 11(10): e1005378, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26426971
14.
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Nature
; 467(7317): 832-8, 2010 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20881960
15.
Sequence kernel association test for survival traits.
Genet Epidemiol
; 38(3): 191-7, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24464521
16.
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.
Hum Mol Genet
; 22(17): 3597-607, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23669352
17.
Familial Hypercholesterolemia Variant and Cardiovascular Risk in Individuals With Elevated Cholesterol.
JAMA Cardiol
; 9(3): 263-271, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38294787
18.
Key variants via Alzheimer's Disease Sequencing Project whole genome sequence data.
medRxiv
; 2023 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37693453
19.
Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer's disease at CPT1A locus.
Clin Epigenetics
; 15(1): 173, 2023 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37891690
20.
Expression quantitative trait methylation analysis elucidates gene regulatory effects of DNA methylation: the Framingham Heart Study.
Sci Rep
; 13(1): 12952, 2023 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37563237